ID   SCOB_MYCTO              Reviewed;         218 AA.
AC   P9WPW2; L0TCQ5; O06166; P63650;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 35.
DE   RecName: Full=Probable succinyl-CoA:3-ketoacid coenzyme A transferase subunit B;
DE            EC=2.8.3.5;
DE   AltName: Full=OXCT B;
DE   AltName: Full=Succinyl-CoA:3-oxoacid CoA-transferase;
GN   Name=scoB; OrderedLocusNames=MT2578;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate;
CC         Xref=Rhea:RHEA:24564, ChEBI:CHEBI:30031, ChEBI:CHEBI:35973,
CC         ChEBI:CHEBI:57292, ChEBI:CHEBI:90726; EC=2.8.3.5;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU10034};
CC   -!- SUBUNIT: Heterodimer of a subunit A and a subunit B. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the 3-oxoacid CoA-transferase subunit B family.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK46882.1; -; Genomic_DNA.
DR   PIR; G70550; G70550.
DR   RefSeq; WP_003412782.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WPW2; -.
DR   SMR; P9WPW2; -.
DR   EnsemblBacteria; AAK46882; AAK46882; MT2578.
DR   GeneID; 45426497; -.
DR   KEGG; mtc:MT2578; -.
DR   PATRIC; fig|83331.31.peg.2780; -.
DR   HOGENOM; CLU_019942_4_1_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0008260; F:3-oxoacid CoA-transferase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR012791; 3-oxoacid_CoA-transf_B.
DR   InterPro; IPR004165; CoA_trans_fam_I.
DR   InterPro; IPR004164; CoA_transf_AS.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   PANTHER; PTHR13707; PTHR13707; 1.
DR   Pfam; PF01144; CoA_trans; 1.
DR   SMART; SM00882; CoA_trans; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
DR   TIGRFAMs; TIGR02428; pcaJ_scoB_fam; 1.
DR   PROSITE; PS01274; COA_TRANSF_2; 1.
PE   3: Inferred from homology;
KW   Transferase.
FT   CHAIN           1..218
FT                   /note="Probable succinyl-CoA:3-ketoacid coenzyme A
FT                   transferase subunit B"
FT                   /id="PRO_0000426882"
FT   ACT_SITE        50
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10034"
SQ   SEQUENCE   218 AA;  22898 MW;  321B0AB5BCBFF7D9 CRC64;
     MSAPGWSRDE MAARVAAEFE DGQYVNLGIG MPTLIPNHIP DGVHVVLHSE NGILGVGPYP
     RREDVDADLI NAGKETVTTL PGAAFFSSST SFGIIRGGHL DVAVLGAMQV SVTGDLANWM
     IPGKMVKGMG GAMDLVHGAR KVIVMMEHTA KDGSPKILER CTLPLTGVGC VDRIVTELAV
     IDVCADGLHL VQTAPGVSVD EVVAKTQPPL VLRDLATQ