ID   SANA_HAEIN              Reviewed;         244 AA.
AC   P45130;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Protein SanA homolog;
GN   Name=sanA; OrderedLocusNames=HI_1262;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Participates in the barrier function of the cell envelope.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Single-pass membrane
CC       protein.
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DR   EMBL; L42023; AAC22915.1; -; Genomic_DNA.
DR   PIR; H64169; H64169.
DR   RefSeq; NP_439417.2; NC_000907.1.
DR   AlphaFoldDB; P45130; -.
DR   EnsemblBacteria; AAC22915; AAC22915; HI_1262.
DR   KEGG; hin:HI_1262; -.
DR   PATRIC; fig|71421.8.peg.1314; -.
DR   eggNOG; COG2949; Bacteria.
DR   HOGENOM; CLU_051474_0_2_6; -.
DR   OMA; YDEPDAM; -.
DR   PhylomeDB; P45130; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   CDD; cd06259; YdcF-like; 1.
DR   InterPro; IPR003848; DUF218.
DR   Pfam; PF02698; DUF218; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..244
FT                   /note="Protein SanA homolog"
FT                   /id="PRO_0000097580"
FT   TOPO_DOM        1..31
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        53..244
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   244 AA;  28188 MW;  23852BB32FFB9696 CRC64;
     MRFTKSIKFS LKCGRFFIMF TTMLVKKFSP KFTALFRTLL YAIFALIILC LLVDRGISFY
     VRDKIFTNID ELPFRPCALV LGTSKYTVSG KPNVYYDSRL MAAKSLIEQQ KVNYLLLSGD
     NRTLQYNEPR AMFRDLRKMG VPKTLMFRDF AGFRTLDSVI RADKIFQVKT FTIVSQKFHC
     ERALLIAQAH NIDAICFVAK QPELHFSTQI REVFARIKAV FDLILGVEPY FLGEPQPLPN
     STTL