SAMP_MUSCA
ID SAMP_MUSCA Reviewed; 9 AA.
AC P19095;
DT 01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1990, sequence version 1.
DT 25-MAY-2022, entry version 60.
DE RecName: Full=Serum amyloid P-component;
DE Short=SAP;
DE Flags: Fragment;
OS Mustelus canis (Smooth dogfish) (Squalus canis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Triakidae;
OC Mustelus.
OX NCBI_TaxID=7812;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=6403520; DOI=10.1016/s0021-9258(18)32750-9;
RA Robey F.A., Tanaka T., Liu T.-Y.;
RT "Isolation and characterization of two major serum proteins from the
RT dogfish, Mustelus canis, C-reactive protein and amyloid P component.";
RL J. Biol. Chem. 258:3889-3894(1983).
CC -!- SUBUNIT: Homopentamer. Pentraxin (or pentaxin) have a discoid
CC arrangement of 5 non-covalently bound subunits.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- DISEASE: Note=SAP is a precursor of amyloid component P which is found
CC in basement membrane and associated with amyloid deposits.
CC -!- SIMILARITY: Belongs to the pentraxin family. {ECO:0000305}.
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DR PIR; B20569; B20569.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amyloid; Direct protein sequencing; Lectin; Secreted.
FT CHAIN 1..>9
FT /note="Serum amyloid P-component"
FT /id="PRO_0000162504"
FT DOMAIN 1..>9
FT /note="Pentraxin (PTX)"
FT NON_TER 9
SQ SEQUENCE 9 AA; 965 MW; D05B5735B3386769 CRC64;
GFPGKSLIF