ID   RSSA_GIAIC              Reviewed;         245 AA.
AC   A8BE86;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03015};
GN   ORFNames=GL50803_7766;
OS   Giardia intestinalis (strain ATCC 50803 / WB clone C6) (Giardia lamblia).
OC   Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX   NCBI_TaxID=184922;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50803 / WB clone C6;
RX   PubMed=17901334; DOI=10.1126/science.1143837;
RA   Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D.,
RA   Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J., Davids B.J.,
RA   Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E., Huse S.M., Kim U.U.,
RA   Lasek-Nesselquist E., Manning G., Nigam A., Nixon J.E.J., Palm D.,
RA   Passamaneck N.E., Prabhu A., Reich C.I., Reiner D.S., Samuelson J.,
RA   Svard S.G., Sogin M.L.;
RT   "Genomic minimalism in the early diverging intestinal parasite Giardia
RT   lamblia.";
RL   Science 317:1921-1926(2007).
CC   -!- FUNCTION: Required for the assembly and/or stability of the 40S
CC       ribosomal subunit. Required for the processing of the 20S rRNA-
CC       precursor to mature 18S rRNA in a late step of the maturation of 40S
CC       ribosomal subunits. {ECO:0000255|HAMAP-Rule:MF_03015}.
CC   -!- SUBUNIT: Component of the small ribosomal subunit. Mature ribosomes
CC       consist of a small (40S) and a large (60S) subunit. The 40S subunit
CC       contains about 33 different proteins and 1 molecule of RNA (18S). The
CC       60S subunit contains about 49 different proteins and 3 molecules of RNA
CC       (25S, 5.8S and 5S). Interacts with ribosomal protein S21.
CC       {ECO:0000255|HAMAP-Rule:MF_03015}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03015}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uS2 family.
CC       {ECO:0000255|HAMAP-Rule:MF_03015}.
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DR   EMBL; AACB02000013; EDO79939.1; -; Genomic_DNA.
DR   RefSeq; XP_001707613.1; XM_001707561.1.
DR   AlphaFoldDB; A8BE86; -.
DR   SMR; A8BE86; -.
DR   STRING; 5741.EDO79939; -.
DR   PRIDE; A8BE86; -.
DR   EnsemblProtists; EDO79939; EDO79939; GL50803_7766.
DR   GeneID; 5700515; -.
DR   KEGG; gla:GL50803_007766; -.
DR   VEuPathDB; GiardiaDB:GL50803_7766; -.
DR   HOGENOM; CLU_058171_2_0_1; -.
DR   InParanoid; A8BE86; -.
DR   OMA; ENKMKRY; -.
DR   OrthoDB; 1129610at2759; -.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR   GO; GO:0000028; P:ribosomal small subunit assembly; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   CDD; cd01425; RPS2; 1.
DR   HAMAP; MF_03015; Ribosomal_S2_euk; 1.
DR   InterPro; IPR001865; Ribosomal_S2.
DR   InterPro; IPR018130; Ribosomal_S2_CS.
DR   InterPro; IPR027498; Ribosomal_S2_euk.
DR   InterPro; IPR005707; Ribosomal_S2_euk/arc.
DR   InterPro; IPR023591; Ribosomal_S2_flav_dom_sf.
DR   PANTHER; PTHR11489; PTHR11489; 1.
DR   Pfam; PF00318; Ribosomal_S2; 2.
DR   PRINTS; PR00395; RIBOSOMALS2.
DR   SUPFAM; SSF52313; SSF52313; 1.
DR   TIGRFAMs; TIGR01012; uS2_euk_arch; 1.
DR   PROSITE; PS00962; RIBOSOMAL_S2_1; 1.
DR   PROSITE; PS00963; RIBOSOMAL_S2_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..245
FT                   /note="40S ribosomal protein SA"
FT                   /id="PRO_0000371655"
FT   REGION          211..245
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        211..237
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   245 AA;  28072 MW;  D44CED80CA410278 CRC64;
     MSTEKTSQAS KEYQLKEADV KKMLVATTHL GVRNIDRRMQ FYIFDRQKDG TFVFNLQKVW
     AKIVFAARIL VTIDDPAEIA VVANRPDAQR AILKFCKYTH ATAFPGRFIP GNFTNRMNPN
     YCEPRLLLVN DPVVDRQAIL EASYVNIPTI SLCNSDANLK FIDVAIPCNN KTPMSIGLIY
     WLLAREVLRL KGSISRTEEW DVKPDLFVAL PEEIPDEEES EDFYDDDEEE DEEFSAGNGN
     LFDEY