ID   RSE1_ASPFU              Reviewed;        1225 AA.
AC   Q4WLI5;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Pre-mRNA-splicing factor rse1;
GN   Name=rse1; ORFNames=AFUA_6G13410;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA   Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA   Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA   Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA   Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA   Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA   Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA   O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA   Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA   Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA   Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA   Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA   Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- FUNCTION: Involved in pre-mRNA splicing and cell cycle control.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RSE1 family. {ECO:0000305}.
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DR   EMBL; AAHF01000006; EAL89179.1; -; Genomic_DNA.
DR   RefSeq; XP_751217.1; XM_746124.1.
DR   AlphaFoldDB; Q4WLI5; -.
DR   SMR; Q4WLI5; -.
DR   STRING; 746128.CADAFUBP00000131; -.
DR   EnsemblFungi; EAL89179; EAL89179; AFUA_6G13410.
DR   GeneID; 3508529; -.
DR   KEGG; afm:AFUA_6G13410; -.
DR   VEuPathDB; FungiDB:Afu6g13410; -.
DR   eggNOG; KOG1898; Eukaryota.
DR   HOGENOM; CLU_003246_0_0_1; -.
DR   InParanoid; Q4WLI5; -.
DR   OMA; FFLVQTE; -.
DR   OrthoDB; 97116at2759; -.
DR   Proteomes; UP000002530; Chromosome 6.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR   GO; GO:0030620; F:U2 snRNA binding; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 3.
DR   InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR   InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR   InterPro; IPR011044; Quino_amine_DH_bsu.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF03178; CPSF_A; 1.
DR   Pfam; PF10433; MMS1_N; 1.
DR   SUPFAM; SSF50969; SSF50969; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT   CHAIN           1..1225
FT                   /note="Pre-mRNA-splicing factor rse1"
FT                   /id="PRO_0000218626"
SQ   SEQUENCE   1225 AA;  135200 MW;  AC4CA4DE2E0F7D1E CRC64;
     MATTSNMFMY SLTIQPPTAI TQAILGQFAG TKEQQIVTAS GSKLTIHRPD PTQGKITPIY
     SQDVFGIIRT LAAFRLAGSS KDYIIIGSDS GRITIIEYVP SQNRFNRIHL ETFGKSGVRR
     VVPGQYLAVD PKGRACLIAS VEKNKLVYVL NRNSQAELTI SSPLEAHKPQ TVVFAMTALD
     VGYENPIFAA LEVDYSEADQ DPTGRAYEES EKLLVYYELD LGLNHVVRKW ADPVDRTASM
     LFQVPGGADG PSGVLVCAED NITYRHSNQD AFRVPIPRRI GATENPERKR SIVAGVMHKM
     RGAFFFLLQT EDGDLFKVTI DMVEDDNGQL TGEVKRLKIK YFDTVPIASS LLILKSGFLY
     VASEAGNHHF YQFEKLGDDD EETEFNSENF PADLSVPCEP VFFQPRGAEN LNLVETLNSL
     NPLIDSKIVN LNEDDAPQIY TVSGSGARSS FRTLKHGLEV SEIVESELPS VPSAVWTTKL
     TRADEFDAYI ILSFANGTLV LSIGETVEEV TDTGFLSTAP TLAVQQLGED SLIQVHPRGI
     RHILADRRVN EWPAPQHRSI VAAATNERQV AVALSSGEIV YFEMDADGTL AEYDERRQMS
     GTVTCLSLGE VPEGRVRSSF LAVGCDDSTV RILSLDPDST LENKSVQALT SAPSALNIMS
     MADSSSGGTT LYLHIGLYSG VYLRTVLDEV TGELSDTRTR FLGAKPVKLF RVSVKGQTAV
     LALSSRPWLG YSDIQTKGFM LTPLDYVGLE WGWNFSSEQC VEGMVGIQAQ NLRIFSIEKL
     DNNILQESIP LSNTPRRMLK HPEQPLFYVI ESDNNVLSPA TRARLIEDSK ARNGETNVLP
     PEDFGYPRAT GHWASCIQIV DPLDAKAVIS TIELEENEAA VSMAAVPFSS QDDETFLVVG
     TAKDMIVNPP SSAGGFIHIY RFQEDGKELE FIHKTKVEEP PLALLGFQGR LLAGIGSTLR
     IYDLGMKQLL RKCQAQVVSK TIVGLQTQGS RIVVSDVRES VTYVVYKYQD NILIPFVDDS
     VSRWTTSTTM VDYETVAGGD KFGNLWLVRC PKKASEEADE DGSGAHLIHE RGYLHGAPNR
     LDLMIHTYTQ DIPTSLHKTQ LVAGGRDILV WTGFQGTIGM LVPFVSREDV DFFQNLEMQL
     ASQCPPLAGR DHLIYRSYYA PVKGVIDGDL CEMYFLLPND TKMMIAAELD RSVREIERKI
     SVRYANEGSV LIILMAIPAS VCKGL