RS14_CRIGR
ID RS14_CRIGR Reviewed; 151 AA.
AC P62265; P06366;
DT 01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=40S ribosomal protein S14;
GN Name=RPS14; Synonyms=EMTB;
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=3839563; DOI=10.1128/mcb.5.7.1655-1659.1985;
RA Rhoads D.D., Roufa D.J.;
RT "Emetine resistance of Chinese hamster cells: structures of wild-type and
RT mutant ribosomal protein S14 mRNAs.";
RL Mol. Cell. Biol. 5:1655-1659(1985).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2267626; DOI=10.1007/bf01233092;
RA Diaz J.J., Rhoads D.D., Roufa D.J.;
RT "Genetic analysis of a vital mammalian housekeeping locus using CHO cells
RT that express a transfected mutant allele.";
RL Somat. Cell Mol. Genet. 16:517-528(1990).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1921707; DOI=10.1093/oxfordjournals.molbev.a040665;
RA Rhoads D.D., Roufa D.J.;
RT "Molecular evolution of the mammalian ribosomal protein gene, RPS14.";
RL Mol. Biol. Evol. 8:503-514(1991).
CC -!- MISCELLANEOUS: Mutations in S14 can lead to resistance to the protein
CC synthesis inhibitor emetine.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS11 family.
CC {ECO:0000305}.
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DR EMBL; M11241; AAA37016.1; -; mRNA.
DR EMBL; M35008; AAA37017.1; -; Genomic_DNA.
DR PIR; A02725; R4HY14.
DR RefSeq; NP_001231448.1; NM_001244519.1.
DR AlphaFoldDB; P62265; -.
DR SMR; P62265; -.
DR STRING; 10029.NP_001231448.1; -.
DR Ensembl; ENSCGRT00001023942; ENSCGRP00001019698; ENSCGRG00001019064.
DR GeneID; 100689292; -.
DR KEGG; cge:100689292; -.
DR CTD; 6208; -.
DR eggNOG; KOG0407; Eukaryota.
DR GeneTree; ENSGT00390000000703; -.
DR OMA; KWGVAHI; -.
DR OrthoDB; 1408000at2759; -.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0014069; C:postsynaptic density; IEA:Ensembl.
DR GO; GO:0048027; F:mRNA 5'-UTR binding; IEA:Ensembl.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:Ensembl.
DR GO; GO:0045182; F:translation regulator activity; IEA:Ensembl.
DR GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0000028; P:ribosomal small subunit assembly; IEA:Ensembl.
DR GO; GO:0006412; P:translation; IEA:Ensembl.
DR Gene3D; 3.30.420.80; -; 1.
DR HAMAP; MF_01310; Ribosomal_S11; 1.
DR InterPro; IPR001971; Ribosomal_S11.
DR InterPro; IPR018102; Ribosomal_S11_CS.
DR InterPro; IPR036967; Ribosomal_S11_sf.
DR PANTHER; PTHR11759; PTHR11759; 1.
DR Pfam; PF00411; Ribosomal_S11; 1.
DR PIRSF; PIRSF002131; Ribosomal_S11; 1.
DR PROSITE; PS00054; RIBOSOMAL_S11; 1.
PE 2: Evidence at transcript level;
KW Isopeptide bond; Phosphoprotein; Ribonucleoprotein; Ribosomal protein;
KW Ubl conjugation.
FT CHAIN 1..151
FT /note="40S ribosomal protein S14"
FT /id="PRO_0000123336"
FT REGION 131..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 16
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P62263"
FT MOD_RES 133
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:P62263"
FT MOD_RES 139
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P62263"
FT CROSSLNK 61
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:P62263"
FT CROSSLNK 63
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:P62263"
FT CROSSLNK 106
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:P62263"
SQ SEQUENCE 151 AA; 16273 MW; 4F4387F9FADAC278 CRC64;
MAPRKGKEKK EEQVISLGPQ VAEGENVFGV CHIFASFNDT FVHVTDLSGK ETICRVTGGM
KVKADRDESS PYAAMLAAQD VAQRCKELGI TALHIKLRAT GGNRTKTPGP GAQSALRALA
RSGMKIGRIE DVTPIPSDST RRKGGRRGRR L
