RPC1_BP186
ID RPC1_BP186 Reviewed; 192 AA.
AC P08707;
DT 01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT 15-JUL-1999, sequence version 2.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Repressor protein CI;
GN Name=CI;
OS Escherichia phage 186 (Bacteriophage 186).
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Caudovirales; Myoviridae; Peduovirinae; Eganvirus.
OX NCBI_TaxID=29252;
OH NCBI_TaxID=562; Escherichia coli.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=186CITSP;
RX PubMed=3806670; DOI=10.1016/0022-2836(86)90257-3;
RA Kalionis B., Dodd I.B., Egan J.B.;
RT "Control of gene expression in the P2-related template coliphages. III. DNA
RT sequence of the major control region of phage 186.";
RL J. Mol. Biol. 191:199-209(1986).
RN [2]
RP SEQUENCE REVISION TO 22.
RX PubMed=2370665; DOI=10.1016/0022-2836(90)90144-b;
RA Dodd I.B., Kalionis B., Egan J.B.;
RT "Control of gene expression in the temperate coliphage 186. VIII. Control
RT of lysis and lysogeny by a transcriptional switch involving face-to-face
RT promoters.";
RL J. Mol. Biol. 214:27-37(1990).
CC -!- FUNCTION: Repressor of lysogeny.
CC -!- SIMILARITY: Belongs to the CI repressor protein family. {ECO:0000305}.
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DR EMBL; U32222; AAC34176.1; -; Genomic_DNA.
DR PIR; S09533; S09533.
DR RefSeq; NP_052279.1; NC_001317.1.
DR PDB; 2FJR; X-ray; 1.95 A; A/B=4-192.
DR PDB; 2FKD; X-ray; 2.70 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N=83-192.
DR PDB; 7JVT; X-ray; 3.16 A; C/D=84-192.
DR PDBsum; 2FJR; -.
DR PDBsum; 2FKD; -.
DR PDBsum; 7JVT; -.
DR SMR; P08707; -.
DR GeneID; 1262440; -.
DR KEGG; vg:1262440; -.
DR EvolutionaryTrace; P08707; -.
DR Proteomes; UP000000369; Genome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR GO; GO:0051259; P:protein complex oligomerization; IEA:InterPro.
DR Gene3D; 1.10.260.40; -; 1.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR032499; Phage_CI_C.
DR InterPro; IPR010744; Phage_CI_repr.
DR Pfam; PF16452; Phage_CI_C; 1.
DR Pfam; PF07022; Phage_CI_repr; 1.
PE 1: Evidence at protein level;
KW 3D-structure; DNA-binding; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..192
FT /note="Repressor protein CI"
FT /id="PRO_0000165292"
FT HELIX 10..21
FT /evidence="ECO:0007829|PDB:2FJR"
FT HELIX 26..32
FT /evidence="ECO:0007829|PDB:2FJR"
FT HELIX 37..45
FT /evidence="ECO:0007829|PDB:2FJR"
FT STRAND 46..48
FT /evidence="ECO:0007829|PDB:2FJR"
FT HELIX 51..61
FT /evidence="ECO:0007829|PDB:2FJR"
FT HELIX 65..70
FT /evidence="ECO:0007829|PDB:2FJR"
FT STRAND 86..94
FT /evidence="ECO:0007829|PDB:2FJR"
FT STRAND 97..106
FT /evidence="ECO:0007829|PDB:2FJR"
FT HELIX 108..110
FT /evidence="ECO:0007829|PDB:2FJR"
FT STRAND 116..123
FT /evidence="ECO:0007829|PDB:2FJR"
FT STRAND 126..131
FT /evidence="ECO:0007829|PDB:2FJR"
FT STRAND 138..145
FT /evidence="ECO:0007829|PDB:2FJR"
FT STRAND 148..157
FT /evidence="ECO:0007829|PDB:2FJR"
FT TURN 158..160
FT /evidence="ECO:0007829|PDB:2FJR"
FT STRAND 161..169
FT /evidence="ECO:0007829|PDB:2FJR"
FT STRAND 171..174
FT /evidence="ECO:0007829|PDB:2FJR"
FT STRAND 177..190
FT /evidence="ECO:0007829|PDB:2FJR"
SQ SEQUENCE 192 AA; 21157 MW; 7A8E300C425794D6 CRC64;
MRIDSLGWSN VDVLDRICEA YGFSQKIQLA NHFDIASSSL SNRYTRGAIS YDFAAHCALE
TGANLQWLLT GEGEAFVNNR ESSDAKRIEG FTLSEEILKS DKQLSVDAQF FTKPLTDGMA
IRSEGKIYFV DKQASLSDGL WLVDIEGAIS IRELTKLPGR KLHVAGGKVP FECGIDDIKT
LGRVVGVYSE VN
