ID   RM02_KLULA              Reviewed;         364 AA.
AC   P48535; Q6CK99;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2004, sequence version 2.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=54S ribosomal protein L2, mitochondrial;
DE   Flags: Precursor;
GN   Name=MRPL2; Synonyms=MRP7; OrderedLocusNames=KLLA0F12386g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Pan C., Sirum-Connolly K., Mason T.L.;
RT   "Essential features of the peptidyl transferase center in the yeast
RT   mitochondrial ribosome.";
RL   (In) Nierhaus K.H. (eds.);
RL   The translational apparatus, pp.587-598, Plenum Press, New York (1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the large subunit of mitochondrial ribosome.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion.
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL27 family.
CC       {ECO:0000305}.
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DR   EMBL; U38369; AAA79723.1; -; Genomic_DNA.
DR   EMBL; CR382126; CAG98348.1; -; Genomic_DNA.
DR   RefSeq; XP_455640.1; XM_455640.1.
DR   AlphaFoldDB; P48535; -.
DR   SMR; P48535; -.
DR   STRING; 28985.XP_455640.1; -.
DR   EnsemblFungi; CAG98348; CAG98348; KLLA0_F12386g.
DR   GeneID; 2895001; -.
DR   KEGG; kla:KLLA0_F12386g; -.
DR   eggNOG; KOG4600; Eukaryota.
DR   HOGENOM; CLU_063752_0_0_1; -.
DR   InParanoid; P48535; -.
DR   OMA; FYLDPFH; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; IEA:EnsemblFungi.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:EnsemblFungi.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   InterPro; IPR001684; Ribosomal_L27.
DR   InterPro; IPR041244; Ribosomal_L27_C.
DR   InterPro; IPR018261; Ribosomal_L27_CS.
DR   PANTHER; PTHR15893; PTHR15893; 1.
DR   Pfam; PF01016; Ribosomal_L27; 1.
DR   Pfam; PF18471; Ribosomal_L27_C; 1.
DR   PRINTS; PR00063; RIBOSOMALL27.
DR   TIGRFAMs; TIGR00062; L27; 1.
DR   PROSITE; PS00831; RIBOSOMAL_L27; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   Transit peptide.
FT   TRANSIT         1..19
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250"
FT   CHAIN           20..364
FT                   /note="54S ribosomal protein L2, mitochondrial"
FT                   /id="PRO_0000030500"
FT   CONFLICT        298
FT                   /note="A -> R (in Ref. 1; AAA79723)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   364 AA;  42635 MW;  29E4452C5659EEF2 CRC64;
     MFSSSWQQVP KFVVQQVRTA TKRAAGSRTS MKDSAGRRLG PKKYEGQATQ VGEIIMRQRG
     TKFYPGENVG IGKDHTLFAL EPGYVRYYLD PFHPGKKFIG VSLYKDVKLP LPHFEPRLRR
     FGKAIIEDEE KAIAEENALP RKIYLLKDEL IKKQQEREIK REELKAEYSK IISDLKVELD
     QQELAFALPY LLRWRTCLKN GFNESDARFN SYYYLEQELK LKMRNQEKSK LDDKLTLLKQ
     VSTKLNESLS FNNKLELTKY ISPEEKNTLK TQLITDLKAI DIKDKNSKKQ VLAKFTDAKN
     FLTLSEEVRL RRKFLKPVKP ETELKKLEEP LKPSKKNLTT RRYNYEQNTI DVITRPKTDF
     LSKL