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RL27_DANRE
ID   RL27_DANRE              Reviewed;         136 AA.
AC   Q7ZV82;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=60S ribosomal protein L27;
GN   Name=rpl27; ORFNames=zgc:56171;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P61353}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P61353}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:P61353}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P61353}. Rough endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:A1XQU5}. Note=Detected on cytosolic polysomes
CC       (By similarity). Detected in ribosomes that are associated with the
CC       rough endoplasmic reticulum (By similarity).
CC       {ECO:0000250|UniProtKB:A1XQU5, ECO:0000250|UniProtKB:P61353}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL27 family.
CC       {ECO:0000305}.
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DR   EMBL; BC045965; AAH45965.1; -; mRNA.
DR   RefSeq; NP_956018.1; NM_199724.1.
DR   AlphaFoldDB; Q7ZV82; -.
DR   SMR; Q7ZV82; -.
DR   BioGRID; 83546; 1.
DR   STRING; 7955.ENSDARP00000117864; -.
DR   PaxDb; Q7ZV82; -.
DR   PRIDE; Q7ZV82; -.
DR   Ensembl; ENSDART00000020311; ENSDARP00000018737; ENSDARG00000015128.
DR   Ensembl; ENSDART00000140518; ENSDARP00000117864; ENSDARG00000015128.
DR   GeneID; 325618; -.
DR   KEGG; dre:325618; -.
DR   CTD; 6155; -.
DR   ZFIN; ZDB-GENE-030131-4343; rpl27.
DR   eggNOG; KOG3418; Eukaryota.
DR   GeneTree; ENSGT00390000010721; -.
DR   HOGENOM; CLU_067359_0_1_1; -.
DR   InParanoid; Q7ZV82; -.
DR   OMA; HPFPYAI; -.
DR   OrthoDB; 1584965at2759; -.
DR   PhylomeDB; Q7ZV82; -.
DR   TreeFam; TF314648; -.
DR   Reactome; R-DRE-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-DRE-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-DRE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-DRE-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-DRE-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-DRE-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-DRE-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q7ZV82; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 3.
DR   Bgee; ENSDARG00000015128; Expressed in pharyngeal gill and 32 other tissues.
DR   ExpressionAtlas; Q7ZV82; baseline and differential.
DR   GO; GO:0098556; C:cytoplasmic side of rough endoplasmic reticulum membrane; ISS:UniProtKB.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0015934; C:large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0030218; P:erythrocyte differentiation; IMP:ZFIN.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd06090; KOW_RPL27; 1.
DR   Gene3D; 2.30.30.770; -; 1.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR041991; KOW_RPL27.
DR   InterPro; IPR038655; L27e_sf.
DR   InterPro; IPR001141; Ribosomal_L27e.
DR   InterPro; IPR018262; Ribosomal_L27e_CS.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR10497; PTHR10497; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF01777; Ribosomal_L27e; 1.
DR   SMART; SM00739; KOW; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   PROSITE; PS01107; RIBOSOMAL_L27E; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Endoplasmic reticulum; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein.
FT   CHAIN           1..136
FT                   /note="60S ribosomal protein L27"
FT                   /id="PRO_0000126081"
FT   DOMAIN          5..40
FT                   /note="KOW"
SQ   SEQUENCE   136 AA;  15782 MW;  37DAF6084E73AA4C CRC64;
     MGKFMKPGKV VMVLAGRYAG RKAVIVKNID DGTADRPYSH ALVAGIDRYP RKVTATMGKK
     KIAKRSKIKA FVKVFNYNHL MPTRYSVDIP LDKTVVNKDV FRDPALKRKA RREAKVKFEE
     RYKTGKNKWF FQKLRF
 
 
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