RL27_DANRE
ID RL27_DANRE Reviewed; 136 AA.
AC Q7ZV82;
DT 10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=60S ribosomal protein L27;
GN Name=rpl27; ORFNames=zgc:56171;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:P61353}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:P61353}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000250|UniProtKB:P61353}. Cytoplasm
CC {ECO:0000250|UniProtKB:P61353}. Rough endoplasmic reticulum
CC {ECO:0000250|UniProtKB:A1XQU5}. Note=Detected on cytosolic polysomes
CC (By similarity). Detected in ribosomes that are associated with the
CC rough endoplasmic reticulum (By similarity).
CC {ECO:0000250|UniProtKB:A1XQU5, ECO:0000250|UniProtKB:P61353}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL27 family.
CC {ECO:0000305}.
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DR EMBL; BC045965; AAH45965.1; -; mRNA.
DR RefSeq; NP_956018.1; NM_199724.1.
DR AlphaFoldDB; Q7ZV82; -.
DR SMR; Q7ZV82; -.
DR BioGRID; 83546; 1.
DR STRING; 7955.ENSDARP00000117864; -.
DR PaxDb; Q7ZV82; -.
DR PRIDE; Q7ZV82; -.
DR Ensembl; ENSDART00000020311; ENSDARP00000018737; ENSDARG00000015128.
DR Ensembl; ENSDART00000140518; ENSDARP00000117864; ENSDARG00000015128.
DR GeneID; 325618; -.
DR KEGG; dre:325618; -.
DR CTD; 6155; -.
DR ZFIN; ZDB-GENE-030131-4343; rpl27.
DR eggNOG; KOG3418; Eukaryota.
DR GeneTree; ENSGT00390000010721; -.
DR HOGENOM; CLU_067359_0_1_1; -.
DR InParanoid; Q7ZV82; -.
DR OMA; HPFPYAI; -.
DR OrthoDB; 1584965at2759; -.
DR PhylomeDB; Q7ZV82; -.
DR TreeFam; TF314648; -.
DR Reactome; R-DRE-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-DRE-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-DRE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-DRE-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-DRE-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-DRE-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-DRE-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:Q7ZV82; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 3.
DR Bgee; ENSDARG00000015128; Expressed in pharyngeal gill and 32 other tissues.
DR ExpressionAtlas; Q7ZV82; baseline and differential.
DR GO; GO:0098556; C:cytoplasmic side of rough endoplasmic reticulum membrane; ISS:UniProtKB.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0015934; C:large ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0030218; P:erythrocyte differentiation; IMP:ZFIN.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd06090; KOW_RPL27; 1.
DR Gene3D; 2.30.30.770; -; 1.
DR InterPro; IPR005824; KOW.
DR InterPro; IPR041991; KOW_RPL27.
DR InterPro; IPR038655; L27e_sf.
DR InterPro; IPR001141; Ribosomal_L27e.
DR InterPro; IPR018262; Ribosomal_L27e_CS.
DR InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR PANTHER; PTHR10497; PTHR10497; 1.
DR Pfam; PF00467; KOW; 1.
DR Pfam; PF01777; Ribosomal_L27e; 1.
DR SMART; SM00739; KOW; 1.
DR SUPFAM; SSF50104; SSF50104; 1.
DR PROSITE; PS01107; RIBOSOMAL_L27E; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Endoplasmic reticulum; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein.
FT CHAIN 1..136
FT /note="60S ribosomal protein L27"
FT /id="PRO_0000126081"
FT DOMAIN 5..40
FT /note="KOW"
SQ SEQUENCE 136 AA; 15782 MW; 37DAF6084E73AA4C CRC64;
MGKFMKPGKV VMVLAGRYAG RKAVIVKNID DGTADRPYSH ALVAGIDRYP RKVTATMGKK
KIAKRSKIKA FVKVFNYNHL MPTRYSVDIP LDKTVVNKDV FRDPALKRKA RREAKVKFEE
RYKTGKNKWF FQKLRF