RIMM_MYCTU
ID RIMM_MYCTU Reviewed; 176 AA.
AC P9WH19; L0TCL1; P66653; Q10824;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 37.
DE RecName: Full=Ribosome maturation factor RimM {ECO:0000255|HAMAP-Rule:MF_00014};
GN Name=rimM {ECO:0000255|HAMAP-Rule:MF_00014}; OrderedLocusNames=Rv2907c;
GN ORFNames=MTCY274.38c;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- FUNCTION: An accessory protein needed during the final step in the
CC assembly of 30S ribosomal subunit, possibly for assembly of the head
CC region. Probably interacts with S19. Essential for efficient processing
CC of 16S rRNA. May be needed both before and after RbfA during the
CC maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits
CC but not for 70S ribosomes. {ECO:0000255|HAMAP-Rule:MF_00014}.
CC -!- SUBUNIT: Binds ribosomal protein S19. {ECO:0000255|HAMAP-
CC Rule:MF_00014}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00014}.
CC -!- DOMAIN: The PRC barrel domain binds ribosomal protein S19.
CC {ECO:0000255|HAMAP-Rule:MF_00014}.
CC -!- SIMILARITY: Belongs to the RimM family. {ECO:0000255|HAMAP-
CC Rule:MF_00014}.
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DR EMBL; AL123456; CCP45709.1; -; Genomic_DNA.
DR PIR; F70927; F70927.
DR RefSeq; NP_217423.1; NC_000962.3.
DR RefSeq; WP_003414726.1; NZ_NVQJ01000006.1.
DR PDB; 7CQ1; NMR; -; A=101-176.
DR PDBsum; 7CQ1; -.
DR AlphaFoldDB; P9WH19; -.
DR SMR; P9WH19; -.
DR STRING; 83332.Rv2907c; -.
DR PaxDb; P9WH19; -.
DR DNASU; 887188; -.
DR GeneID; 45426894; -.
DR GeneID; 887188; -.
DR KEGG; mtu:Rv2907c; -.
DR TubercuList; Rv2907c; -.
DR eggNOG; COG0806; Bacteria.
DR OMA; DEFYHAD; -.
DR PhylomeDB; P9WH19; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005840; C:ribosome; IEA:InterPro.
DR GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR GO; GO:0042274; P:ribosomal small subunit biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR Gene3D; 2.40.30.60; -; 1.
DR HAMAP; MF_00014; Ribosome_mat_RimM; 1.
DR InterPro; IPR011961; 16S_RimM.
DR InterPro; IPR027275; PRC-brl_dom.
DR InterPro; IPR011033; PRC_barrel-like_sf.
DR InterPro; IPR002676; RimM_N.
DR InterPro; IPR036976; RimM_N_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR Pfam; PF05239; PRC; 1.
DR Pfam; PF01782; RimM; 1.
DR SUPFAM; SSF50346; SSF50346; 1.
DR SUPFAM; SSF50447; SSF50447; 1.
DR TIGRFAMs; TIGR02273; 16S_RimM; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Chaperone; Cytoplasm; Reference proteome;
KW Ribosome biogenesis.
FT CHAIN 1..176
FT /note="Ribosome maturation factor RimM"
FT /id="PRO_0000163320"
FT DOMAIN 100..172
FT /note="PRC barrel"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00014"
FT HELIX 105..108
FT /evidence="ECO:0007829|PDB:7CQ1"
FT STRAND 111..115
FT /evidence="ECO:0007829|PDB:7CQ1"
FT STRAND 122..126
FT /evidence="ECO:0007829|PDB:7CQ1"
FT STRAND 131..139
FT /evidence="ECO:0007829|PDB:7CQ1"
FT STRAND 141..149
FT /evidence="ECO:0007829|PDB:7CQ1"
FT TURN 151..153
FT /evidence="ECO:0007829|PDB:7CQ1"
FT STRAND 156..158
FT /evidence="ECO:0007829|PDB:7CQ1"
FT TURN 159..162
FT /evidence="ECO:0007829|PDB:7CQ1"
FT STRAND 163..166
FT /evidence="ECO:0007829|PDB:7CQ1"
FT TURN 170..173
FT /evidence="ECO:0007829|PDB:7CQ1"
SQ SEQUENCE 176 AA; 18616 MW; 3CB6B02306ADC420 CRC64;
MELVVGRVVK SHGVTGEVVV EIRTDDPADR FAPGTRLRAK GPFDGGAEGS AVSYVIESVR
QHGGRLLVRL AGVADRDAAD ALRGSLFVID ADDLPPIDEP DTYYDHQLVG LMVQTATGEG
VGVVTEVVHT AAGELLAVKR DSDEVLVPFV RAIVTSVSLD DGIVEIDPPH GLLNLE
