RFL3S_HUMAN
ID RFL3S_HUMAN Reviewed; 107 AA.
AC P0C7P2; Q5TI83; Q5TI84;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-JUN-2008, sequence version 1.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=Putative protein RFPL3S;
DE AltName: Full=RFPL3 antisense RNA 1;
DE AltName: Full=RFPL3 antisense gene protein 1;
DE AltName: Full=Ret finger protein-like 3 antisense gene protein;
GN Name=RFPL3S; Synonyms=RFPL3-AS1;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RX PubMed=10508838; DOI=10.1101/gr.9.9.803;
RA Seroussi E., Kedra D., Pan H.-Q., Peyrad M., Schwartz C., Scambler P.,
RA Donnai D., Roe B.A., Dumanski J.P.;
RT "Duplications on human chromosome 22 reveal a novel Ret finger protein-like
RT gene family with sense and endogenous antisense transcripts.";
RL Genome Res. 9:803-814(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15461802; DOI=10.1186/gb-2004-5-10-r84;
RA Collins J.E., Wright C.L., Edwards C.A., Davis M.P., Grinham J.A.,
RA Cole C.G., Goward M.E., Aguado B., Mallya M., Mokrab Y., Huckle E.J.,
RA Beare D.M., Dunham I.;
RT "A genome annotation-driven approach to cloning the human ORFeome.";
RL Genome Biol. 5:R84.1-R84.11(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=10591208; DOI=10.1038/990031;
RA Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M.,
RA Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C.,
RA Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E.,
RA Bridgeman A.M., Buck D., Burgess J., Burrill W.D., Burton J., Carder C.,
RA Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G.,
RA Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V.,
RA Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M.,
RA Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A.,
RA Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C.,
RA Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E.,
RA Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F.,
RA Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M.,
RA Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A.,
RA Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D.,
RA Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y.,
RA Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S.,
RA Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E.,
RA Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L.,
RA Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L.,
RA Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N.,
RA Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A.,
RA Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L.,
RA Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P.,
RA Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P.,
RA Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q.,
RA Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J.,
RA Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J.,
RA Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D.,
RA Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T.,
RA Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P.,
RA Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K.,
RA Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R.,
RA Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L.,
RA McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J.,
RA Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E.,
RA Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P.,
RA Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y.,
RA Wright H.;
RT "The DNA sequence of human chromosome 22.";
RL Nature 402:489-495(1999).
CC -!- TISSUE SPECIFICITY: Strongly expressed in the testis and weakly in
CC brain, placenta and pancreas. {ECO:0000269|PubMed:10508838}.
CC -!- MISCELLANEOUS: The gene encoding RFPL3S is located on the opposite
CC strand of the gene encoding RFPL3. Its transcription may play a role in
CC RFPL3 transcription regulation.
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DR EMBL; AJ010233; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; CR456565; CAG30451.1; -; mRNA.
DR EMBL; AL021937; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; P0C7P2; -.
DR STRING; 9606.ENSP00000482492; -.
DR BioMuta; RFPL3S; -.
DR PRIDE; P0C7P2; -.
DR UCSC; uc062dnc.1; human.
DR GeneCards; RFPL3S; -.
DR HGNC; HGNC:9981; RFPL3S.
DR MIM; 605971; gene.
DR neXtProt; NX_P0C7P2; -.
DR HOGENOM; CLU_175681_0_0_1; -.
DR TreeFam; TF341410; -.
DR ChiTaRS; RFPL3S; human.
DR Pharos; P0C7P2; Tdark.
DR PRO; PR:P0C7P2; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; P0C7P2; protein.
DR Genevisible; P0C7P2; HS.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..107
FT /note="Putative protein RFPL3S"
FT /id="PRO_0000341582"
SQ SEQUENCE 107 AA; 11739 MW; B7A57564B5837B4F CRC64;
MQTDTSNLSA RSCRFCVMSP LRTLLRSSEM RRKLLAVSAS KVISTVKRKT SCSASGQKPT
PCLSSTSKAQ ISPDFSFFNS VSSSKIKTFH EETSLFQIFI GMLCGNT
