ID   REP1_KLULC              Reviewed;         415 AA.
AC   P13775;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Trans-acting factor B;
DE   AltName: Full=REP1;
GN   Name=B;
OS   Kluyveromyces lactis (Yeast) (Candida sphaerica).
OG   Plasmid pKD1.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=28985;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 56496 / CBS 2105 / CLIB 601 / NRRL Y-8278;
RX   PubMed=3520486; DOI=10.1093/nar/14.11.4471;
RA   Chen X.J., Saliola M., Falcone C., Bianchi M.M., Fukuhara H.;
RT   "Sequence organization of the circular plasmid pKD1 from the yeast
RT   Kluyveromyces drosophilarum.";
RL   Nucleic Acids Res. 14:4471-4481(1986).
CC   -!- FUNCTION: Plasmid partition require REP1, REP2, and a cis-acting DNA
CC       sequence (known as STB). REP1 may act by intercalating in the yeast
CC       nuclear matrix and binding STB either directly or via REP2.
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DR   EMBL; X03961; CAA27593.1; -; Genomic_DNA.
DR   PIR; S28088; S28088.
DR   AlphaFoldDB; P13775; -.
DR   GO; GO:0030541; P:plasmid partitioning; IEA:UniProtKB-KW.
DR   InterPro; IPR008897; Rep_fungi.
DR   Pfam; PF05797; Rep_4; 1.
PE   4: Predicted;
KW   Plasmid; Plasmid partition.
FT   CHAIN           1..415
FT                   /note="Trans-acting factor B"
FT                   /id="PRO_0000150893"
SQ   SEQUENCE   415 AA;  48000 MW;  D2800957245AE897 CRC64;
     MSAPSESSET AAPLLSDLSP EEQKGVQQVR EIYRALLDSF KFKNEYNAYD PLNNTIITQH
     GSYEVPEAFA QCTYLAQIYV SYKINSLPYQ TYIKDLEWIS PAEVYKLIME RLQKNKYFLR
     KQVQAMEKIK VLLCPSPELL ENNYVDDNLK ISSHKVTQRH PEKVYDLMTY QEIADGIDDF
     FSLLEMPNLS LAFVNKTSIK LNISCSGANN HIGSFIGRTA RTIRHYWIKN AILEFADYKK
     KTVPYPFVGP PRDPGLFEHI VDDCSTGAPI NWDDFSIDSY ASYVTVMEHL EEVVELTDRH
     RRVIEYLGMY IASDLHEEGK LTRARKLDRT TLFHTVRDVL LHDGSYTRHK GVRCLDNGSV
     RVSIRLKHRQ LTATWIELEP IIENGEVKDV MFKLSTRVQY TEENENETRP ESSSE