RCP1_SYNY3
ID RCP1_SYNY3 Reviewed; 147 AA.
AC Q55169;
DT 11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 139.
DE RecName: Full=Response regulator Rcp1;
GN Name=rcp1; OrderedLocusNames=slr0474;
OS Synechocystis sp. (strain PCC 6803 / Kazusa).
OC Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC unclassified Synechocystis.
OX NCBI_TaxID=1111708;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27184 / PCC 6803 / N-1;
RX PubMed=8590279; DOI=10.1093/dnares/2.4.153;
RA Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N.,
RA Sugiura M., Tabata S.;
RT "Sequence analysis of the genome of the unicellular cyanobacterium
RT Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region
RT from map positions 64% to 92% of the genome.";
RL DNA Res. 2:153-166(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6803 / Kazusa;
RX PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence analysis of the genome of the unicellular cyanobacterium
RT Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT genome and assignment of potential protein-coding regions.";
RL DNA Res. 3:109-136(1996).
RN [3]
RP PHOSPHORYLATION AT ASP-68, AND MUTAGENESIS OF ASP-68.
RX PubMed=9278513; DOI=10.1126/science.277.5331.1505;
RA Yeh K.-C., Wu S.-H., Murphy J.T., Lagarias J.C.;
RT "A cyanobacterial phytochrome two-component light sensory system.";
RL Science 277:1505-1508(1997).
CC -!- FUNCTION: Forms a two-component system with Cph1 in which it acts as
CC receiver substrate.
CC -!- INTERACTION:
CC Q55169; Q55168: cph1; NbExp=2; IntAct=EBI-766949, EBI-594457;
CC -!- PTM: Phosphorylated by Cph1. {ECO:0000269|PubMed:9278513}.
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DR EMBL; BA000022; BAA10308.1; -; Genomic_DNA.
DR PIR; S74390; S74390.
DR PDB; 1I3C; X-ray; 1.90 A; A/B=1-147.
DR PDB; 1JLK; X-ray; 2.30 A; A/B=1-147.
DR PDBsum; 1I3C; -.
DR PDBsum; 1JLK; -.
DR AlphaFoldDB; Q55169; -.
DR SMR; Q55169; -.
DR IntAct; Q55169; 4.
DR STRING; 1148.1001166; -.
DR PaxDb; Q55169; -.
DR EnsemblBacteria; BAA10308; BAA10308; BAA10308.
DR KEGG; syn:slr0474; -.
DR eggNOG; COG0784; Bacteria.
DR InParanoid; Q55169; -.
DR OMA; FEKFWFS; -.
DR PhylomeDB; Q55169; -.
DR EvolutionaryTrace; Q55169; -.
DR Proteomes; UP000001425; Chromosome.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Phosphoprotein; Reference proteome;
KW Two-component regulatory system.
FT CHAIN 1..147
FT /note="Response regulator Rcp1"
FT /id="PRO_0000081208"
FT DOMAIN 10..135
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT MOD_RES 68
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169,
FT ECO:0000269|PubMed:9278513"
FT MUTAGEN 68
FT /note="D->A: Unable to be phosphorylated by cph1."
FT /evidence="ECO:0000269|PubMed:9278513"
FT STRAND 9..14
FT /evidence="ECO:0007829|PDB:1I3C"
FT HELIX 18..29
FT /evidence="ECO:0007829|PDB:1I3C"
FT STRAND 35..40
FT /evidence="ECO:0007829|PDB:1I3C"
FT HELIX 43..50
FT /evidence="ECO:0007829|PDB:1I3C"
FT HELIX 54..56
FT /evidence="ECO:0007829|PDB:1I3C"
FT STRAND 63..67
FT /evidence="ECO:0007829|PDB:1I3C"
FT STRAND 72..74
FT /evidence="ECO:0007829|PDB:1I3C"
FT HELIX 76..85
FT /evidence="ECO:0007829|PDB:1I3C"
FT TURN 87..91
FT /evidence="ECO:0007829|PDB:1I3C"
FT STRAND 94..99
FT /evidence="ECO:0007829|PDB:1I3C"
FT HELIX 103..111
FT /evidence="ECO:0007829|PDB:1I3C"
FT STRAND 115..119
FT /evidence="ECO:0007829|PDB:1I3C"
FT HELIX 124..138
FT /evidence="ECO:0007829|PDB:1I3C"
FT TURN 139..141
FT /evidence="ECO:0007829|PDB:1I3C"
SQ SEQUENCE 147 AA; 16609 MW; C854E8036C9FD58E CRC64;
MSDESNPPKV ILLVEDSKAD SRLVQEVLKT STIDHELIIL RDGLAAMAFL QQQGEYENSP
RPNLILLDLN LPKKDGREVL AEIKQNPDLK RIPVVVLTTS HNEDDVIASY ELHVNCYLTK
SRNLKDLFKM VQGIESFWLE TVTLPAA
