ID   RCNR_SHIF8              Reviewed;          90 AA.
AC   Q0T334;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Transcriptional repressor RcnR;
GN   Name=rcnR; OrderedLocusNames=SFV_2160;
OS   Shigella flexneri serotype 5b (strain 8401).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=373384;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=8401;
RX   PubMed=16822325; DOI=10.1186/1471-2164-7-173;
RA   Nie H., Yang F., Zhang X., Yang J., Chen L., Wang J., Xiong Z., Peng J.,
RA   Sun L., Dong J., Xue Y., Xu X., Chen S., Yao Z., Shen Y., Jin Q.;
RT   "Complete genome sequence of Shigella flexneri 5b and comparison with
RT   Shigella flexneri 2a.";
RL   BMC Genomics 7:173-173(2006).
CC   -!- FUNCTION: Repressor of rcnA expression. Acts by binding specifically to
CC       the rcnA promoter in the absence of nickel and cobalt. In the presence
CC       of one of these metals, it has a weaker affinity for rcnA promoter (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FrmR/RcnR family. {ECO:0000305}.
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DR   EMBL; CP000266; ABF04281.1; -; Genomic_DNA.
DR   RefSeq; WP_000019944.1; NC_008258.1.
DR   AlphaFoldDB; Q0T334; -.
DR   SMR; Q0T334; -.
DR   EnsemblBacteria; ABF04281; ABF04281; SFV_2160.
DR   GeneID; 67417885; -.
DR   KEGG; sfv:SFV_2160; -.
DR   HOGENOM; CLU_130332_3_0_6; -.
DR   OMA; EHECAEI; -.
DR   BioCyc; SFLE373384:SFV_RS12105-MON; -.
DR   Proteomes; UP000000659; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProt.
DR   Gene3D; 1.20.58.1000; -; 1.
DR   InterPro; IPR003735; Metal_Tscrpt_repr.
DR   InterPro; IPR038390; Metal_Tscrpt_repr_sf.
DR   PANTHER; PTHR33677; PTHR33677; 1.
DR   Pfam; PF02583; Trns_repr_metal; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..90
FT                   /note="Transcriptional repressor RcnR"
FT                   /id="PRO_0000332705"
SQ   SEQUENCE   90 AA;  10134 MW;  BEF3E5AE971AA2F6 CRC64;
     MSHTIRDKQK LKARASKIQG QVVALKKMLD EPHECAAVLQ QIAAIRGAVN GLMREVIKGH
     LTEHIVHQGD ELKREEDLDV VLKVLDSYIK