ID   RCNR_SHIDS              Reviewed;          90 AA.
AC   Q32E99;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Transcriptional repressor RcnR;
GN   Name=rcnR; OrderedLocusNames=SDY_2279;
OS   Shigella dysenteriae serotype 1 (strain Sd197).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300267;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sd197;
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J.,
RA   Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J.,
RA   Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J.,
RA   Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic agents of
RT   bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- FUNCTION: Repressor of rcnA expression. Acts by binding specifically to
CC       the rcnA promoter in the absence of nickel and cobalt. In the presence
CC       of one of these metals, it has a weaker affinity for rcnA promoter (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FrmR/RcnR family. {ECO:0000305}.
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DR   EMBL; CP000034; ABB62356.1; -; Genomic_DNA.
DR   RefSeq; WP_000019944.1; NC_007606.1.
DR   RefSeq; YP_403847.1; NC_007606.1.
DR   AlphaFoldDB; Q32E99; -.
DR   SMR; Q32E99; -.
DR   STRING; 300267.SDY_2279; -.
DR   EnsemblBacteria; ABB62356; ABB62356; SDY_2279.
DR   GeneID; 67417885; -.
DR   KEGG; sdy:SDY_2279; -.
DR   PATRIC; fig|300267.13.peg.2752; -.
DR   HOGENOM; CLU_130332_3_0_6; -.
DR   OMA; EHECAEI; -.
DR   Proteomes; UP000002716; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProt.
DR   Gene3D; 1.20.58.1000; -; 1.
DR   InterPro; IPR003735; Metal_Tscrpt_repr.
DR   InterPro; IPR038390; Metal_Tscrpt_repr_sf.
DR   PANTHER; PTHR33677; PTHR33677; 1.
DR   Pfam; PF02583; Trns_repr_metal; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..90
FT                   /note="Transcriptional repressor RcnR"
FT                   /id="PRO_0000332704"
SQ   SEQUENCE   90 AA;  10134 MW;  BEF3E5AE971AA2F6 CRC64;
     MSHTIRDKQK LKARASKIQG QVVALKKMLD EPHECAAVLQ QIAAIRGAVN GLMREVIKGH
     LTEHIVHQGD ELKREEDLDV VLKVLDSYIK