RCNR_SALTY
ID RCNR_SALTY Reviewed; 90 AA.
AC Q7CPV3;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Transcriptional repressor RcnR;
GN Name=rcnR; OrderedLocusNames=STM3023;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Repressor of rcnA expression. Acts by binding specifically to
CC the rcnA promoter in the absence of nickel and cobalt. In the presence
CC of one of these metals, it has a weaker affinity for rcnA promoter (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the FrmR/RcnR family. {ECO:0000305}.
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DR EMBL; AE006468; AAL21899.1; -; Genomic_DNA.
DR RefSeq; NP_461940.1; NC_003197.2.
DR RefSeq; WP_000019953.1; NC_003197.2.
DR AlphaFoldDB; Q7CPV3; -.
DR SMR; Q7CPV3; -.
DR STRING; 99287.STM3023; -.
DR PaxDb; Q7CPV3; -.
DR EnsemblBacteria; AAL21899; AAL21899; STM3023.
DR GeneID; 1254546; -.
DR KEGG; stm:STM3023; -.
DR PATRIC; fig|99287.12.peg.3199; -.
DR HOGENOM; CLU_130332_3_0_6; -.
DR OMA; EHECAEI; -.
DR PhylomeDB; Q7CPV3; -.
DR BioCyc; SENT99287:STM3023-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProt.
DR Gene3D; 1.20.58.1000; -; 1.
DR InterPro; IPR003735; Metal_Tscrpt_repr.
DR InterPro; IPR038390; Metal_Tscrpt_repr_sf.
DR PANTHER; PTHR33677; PTHR33677; 1.
DR Pfam; PF02583; Trns_repr_metal; 1.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..90
FT /note="Transcriptional repressor RcnR"
FT /id="PRO_0000332703"
SQ SEQUENCE 90 AA; 10208 MW; 7C49F93134917AA5 CRC64;
MSHTIRDKQK LKARTSKIQG QVIALKKMLD EPHECAAVLQ QIAAIRGAVN GLMREVIKGH
LTEHIVHQSD EARREEDLDV ILKVLDSYIK