ID   RAD52_DEBHA             Reviewed;         573 AA.
AC   Q6BJ51;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=DNA repair and recombination protein RAD52;
GN   Name=RAD52; OrderedLocusNames=DEHA2G05148g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in DNA double-strand break (DSB) repair and
CC       recombination. Promotes the annealing of complementary single-stranded
CC       DNA and by stimulation of the RAD51 recombinase (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Part of a complex that includes RAD51, RAD52 and RAD59.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RAD52 family. {ECO:0000305}.
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DR   EMBL; CR382139; CAG90227.1; -; Genomic_DNA.
DR   RefSeq; XP_461770.1; XM_461770.1.
DR   AlphaFoldDB; Q6BJ51; -.
DR   SMR; Q6BJ51; -.
DR   STRING; 4959.XP_461770.1; -.
DR   EnsemblFungi; CAG90227; CAG90227; DEHA2G05148g.
DR   GeneID; 2904646; -.
DR   KEGG; dha:DEHA2G05148g; -.
DR   VEuPathDB; FungiDB:DEHA2G05148g; -.
DR   eggNOG; KOG4141; Eukaryota.
DR   HOGENOM; CLU_011431_3_1_1; -.
DR   InParanoid; Q6BJ51; -.
DR   OMA; LDDSFMF; -.
DR   OrthoDB; 1572665at2759; -.
DR   Proteomes; UP000000599; Chromosome G.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.390.80; -; 1.
DR   InterPro; IPR041247; Rad52_fam.
DR   InterPro; IPR007232; Rad52_Rad59_Rad22.
DR   InterPro; IPR042525; Rad52_Rad59_Rad22_sf.
DR   PANTHER; PTHR12132; PTHR12132; 1.
DR   Pfam; PF04098; Rad52_Rad22; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleus;
KW   Reference proteome.
FT   CHAIN           1..573
FT                   /note="DNA repair and recombination protein RAD52"
FT                   /id="PRO_0000173886"
FT   DNA_BIND        171..175
FT                   /evidence="ECO:0000250"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          228..330
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          388..408
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          446..573
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        229..326
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        453..468
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        486..503
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        526..573
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   573 AA;  63574 MW;  8863D1C6C7C97DAB CRC64;
     MNTNNNSSGS NGPTSNSASS MYNYTHFKDT KYKNAQGTPN RNFQPVPYTE EEHQRIQYLL
     DKVLGPEYVS FRPGGGGQKV SYIEGWRALN LANEIFGFNG WCSELISSQV DYFDTHGNTG
     RISMGLSVVV RITIKDGTYH EDFGYGYIDN AKNKAMAFEK CKKEAFTDGL KRCLRCFGNV
     LGNCLYDRTI ISKIQKVRLP APELEADNFH RDPLIVQREM KKKQTVGVNI HESAENNTDN
     TNNIPKGNDD NGATNSNENN SNNVHSKQKN SATSLQTPIS NRNFNIPNST SQHRDNNTKP
     RASHPSQPGG PQQHSKTSSN NTPAPKNYDI VGDFDDSLVF SDDLPMDDDE MSHNDGLDDY
     ELQMLIHKNR QNGGTDDPAL IARSSYAENN ENSNSSGEVN PTNNSVQEIP DQPALFVSAK
     RADALQQAPK DATKIPQFDA KYVSPNIRRT LDHSKSVPVR RSEISQAPHD KPRTNIGPPK
     LLNRASPGPT ISNSNTNNLG KRMIGLPPSQ KPPYKRRHQD ASLSQRSKPD ETSQPSSKAV
     PQDTNPSKDK ENQPARVASS KNLEDINNMA QVT