ID   RACA_BACAN              Reviewed;         180 AA.
AC   Q81QX8; Q6HZ44; Q6KT43;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=Chromosome-anchoring protein RacA {ECO:0000255|HAMAP-Rule:MF_01170};
GN   Name=racA {ECO:0000255|HAMAP-Rule:MF_01170};
GN   OrderedLocusNames=BA_2287, GBAA_2287, BAS2133;
OS   Bacillus anthracis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1392;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames / isolate Porton;
RX   PubMed=12721629; DOI=10.1038/nature01586;
RA   Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T.,
RA   Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R.,
RA   Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M.,
RA   Kolonay J.F., Beanan M.J., Dodson R.J., Brinkac L.M., Gwinn M.L.,
RA   DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C.,
RA   Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y.,
RA   Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M.,
RA   Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E.,
RA   White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M.,
RA   Hanna P.C., Kolstoe A.-B., Fraser C.M.;
RT   "The genome sequence of Bacillus anthracis Ames and comparison to closely
RT   related bacteria.";
RL   Nature 423:81-86(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames ancestor;
RX   PubMed=18952800; DOI=10.1128/jb.01347-08;
RA   Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D.,
RA   Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.;
RT   "The complete genome sequence of Bacillus anthracis Ames 'Ancestor'.";
RL   J. Bacteriol. 191:445-446(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sterne;
RA   Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K.,
RA   Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R.,
RA   Richardson P., Rubin E., Tice H.;
RT   "Complete genome sequence of Bacillus anthracis Sterne.";
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the formation of axial filaments and for
CC       anchoring the origin regions at the cell poles in sporulating cells,
CC       thus ensuring proper chromosome segregation in the prespore. Binds in a
CC       dispersed manner throughout the chromosome but preferentially to sites
CC       clustered in the origin portion of the chromosome, causing condensation
CC       of the chromosome and its remodeling into an elongated, anchored
CC       structure. {ECO:0000255|HAMAP-Rule:MF_01170}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01170}.
CC       Note=Localizes to cell poles and nucleoid. {ECO:0000255|HAMAP-
CC       Rule:MF_01170}.
CC   -!- SIMILARITY: Belongs to the RacA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01170}.
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DR   EMBL; AE016879; AAP26158.1; -; Genomic_DNA.
DR   EMBL; AE017334; AAT31411.1; -; Genomic_DNA.
DR   EMBL; AE017225; AAT54445.1; -; Genomic_DNA.
DR   RefSeq; NP_844672.1; NC_003997.3.
DR   RefSeq; WP_000456010.1; NZ_WXXJ01000017.1.
DR   RefSeq; YP_028394.1; NC_005945.1.
DR   AlphaFoldDB; Q81QX8; -.
DR   SMR; Q81QX8; -.
DR   STRING; 260799.BAS2133; -.
DR   DNASU; 1089233; -.
DR   EnsemblBacteria; AAP26158; AAP26158; BA_2287.
DR   EnsemblBacteria; AAT31411; AAT31411; GBAA_2287.
DR   GeneID; 45022176; -.
DR   KEGG; ban:BA_2287; -.
DR   KEGG; bar:GBAA_2287; -.
DR   KEGG; bat:BAS2133; -.
DR   PATRIC; fig|198094.11.peg.2257; -.
DR   eggNOG; COG0789; Bacteria.
DR   HOGENOM; CLU_111022_0_0_9; -.
DR   OMA; WVKQLNL; -.
DR   Proteomes; UP000000427; Chromosome.
DR   Proteomes; UP000000594; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008356; P:asymmetric cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-UniRule.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01170; RacA; 1.
DR   InterPro; IPR023522; Chrosome_anchoring_RacA.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Coiled coil; Cytoplasm;
KW   DNA-binding; Reference proteome; Sporulation.
FT   CHAIN           1..180
FT                   /note="Chromosome-anchoring protein RacA"
FT                   /id="PRO_0000224150"
FT   DNA_BIND        5..25
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01170"
FT   COILED          90..150
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01170"
SQ   SEQUENCE   180 AA;  21311 MW;  33DB01EC40EE97E8 CRC64;
     MEYKTPFIAK KLGVSPKAVV RIAQQLNLTI EKNKYGHFIF TQDDLDQMLE YHRSQIEQSQ
     NTHPTQKTSS NDVEELKTQV NTIVQNISSH DFEQLAAQLN TITRRLDRME EQMQDKANDV
     VTYQLLQHRR EMEEMLERIQ KLEAGLKKEE PIYITPDTKP TYEREKKPKR RKMIFSIFGL