ID   RACA_ALKCK              Reviewed;         171 AA.
AC   Q5WGB8;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Chromosome-anchoring protein RacA {ECO:0000255|HAMAP-Rule:MF_01170};
GN   Name=racA {ECO:0000255|HAMAP-Rule:MF_01170}; OrderedLocusNames=ABC2052;
OS   Alkalihalobacillus clausii (strain KSM-K16) (Bacillus clausii).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX   NCBI_TaxID=66692;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KSM-K16;
RA   Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y.,
RA   Kawai S., Ito S., Horikoshi K.;
RT   "The complete genome sequence of the alkaliphilic Bacillus clausii KSM-
RT   K16.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the formation of axial filaments and for
CC       anchoring the origin regions at the cell poles in sporulating cells,
CC       thus ensuring proper chromosome segregation in the prespore. Binds in a
CC       dispersed manner throughout the chromosome but preferentially to sites
CC       clustered in the origin portion of the chromosome, causing condensation
CC       of the chromosome and its remodeling into an elongated, anchored
CC       structure. {ECO:0000255|HAMAP-Rule:MF_01170}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01170}.
CC       Note=Localizes to cell poles and nucleoid. {ECO:0000255|HAMAP-
CC       Rule:MF_01170}.
CC   -!- SIMILARITY: Belongs to the RacA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01170}.
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DR   EMBL; AP006627; BAD64587.1; -; Genomic_DNA.
DR   RefSeq; WP_011246895.1; NC_006582.1.
DR   AlphaFoldDB; Q5WGB8; -.
DR   STRING; 66692.ABC2052; -.
DR   EnsemblBacteria; BAD64587; BAD64587; ABC2052.
DR   KEGG; bcl:ABC2052; -.
DR   eggNOG; COG0789; Bacteria.
DR   HOGENOM; CLU_111022_0_0_9; -.
DR   OMA; WVKQLNL; -.
DR   OrthoDB; 1287443at2; -.
DR   Proteomes; UP000001168; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008356; P:asymmetric cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-UniRule.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01170; RacA; 1.
DR   InterPro; IPR023522; Chrosome_anchoring_RacA.
DR   InterPro; IPR009061; DNA-bd_dom_put_sf.
DR   InterPro; IPR000551; MerR-type_HTH_dom.
DR   Pfam; PF13411; MerR_1; 1.
DR   SUPFAM; SSF46955; SSF46955; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Coiled coil; Cytoplasm;
KW   DNA-binding; Reference proteome; Sporulation.
FT   CHAIN           1..171
FT                   /note="Chromosome-anchoring protein RacA"
FT                   /id="PRO_0000224154"
FT   DNA_BIND        3..23
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01170"
FT   COILED          77..105
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01170"
SQ   SEQUENCE   171 AA;  20307 MW;  F7A5C211EA1367C7 CRC64;
     MKTKEMSEAI GVNPTTIQRW TKYFKIDCDV TEQGHFLYTE KHLQLFKKIK RELDEGKRMK
     DINLNERQGQ GEPSVPTKQY EAKLEKMLVQ VDALEEKLAT KADDVVSYQL LKHRSELDEM
     MKLVGTLEDR LLFIEKRMMS HHHQEKQVVN EHTPKKIKRG PWRSFMNLFA F