ID   RAB2A_MAIZE             Reviewed;         209 AA.
AC   P49103; B6SI49;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   18-SEP-2019, sequence version 2.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Ras-related protein Rab-2-A;
GN   Name=RAB2A;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Laughner B.J., Ferl R.J., Almira E.C.;
RL   Submitted (MAR-1995) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=18937034; DOI=10.1007/s11103-008-9415-4;
RA   Alexandrov N.N., Brover V.V., Freidin S., Troukhan M.E., Tatarinova T.V.,
RA   Zhang H., Swaller T.J., Lu Y.-P., Bouck J., Flavell R.B., Feldmann K.A.;
RT   "Insights into corn genes derived from large-scale cDNA sequencing.";
RL   Plant Mol. Biol. 69:179-194(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. B73;
RX   PubMed=19936069; DOI=10.1371/journal.pgen.1000740;
RA   Soderlund C., Descour A., Kudrna D., Bomhoff M., Boyd L., Currie J.,
RA   Angelova A., Collura K., Wissotski M., Ashley E., Morrow D., Fernandes J.,
RA   Walbot V., Yu Y.;
RT   "Sequencing, mapping, and analysis of 27,455 maize full-length cDNAs.";
RL   PLoS Genet. 5:E1000740-E1000740(2009).
CC   -!- FUNCTION: Protein transport. Probably involved in vesicular traffic.
CC       {ECO:0000250|UniProtKB:P61019}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000250|UniProtKB:P61019}; Lipid-anchor
CC       {ECO:0000250|UniProtKB:P61019}. Golgi apparatus membrane
CC       {ECO:0000250|UniProtKB:P61019}; Lipid-anchor
CC       {ECO:0000250|UniProtKB:P61019}.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC       {ECO:0000305}.
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DR   EMBL; U22432; AAA63901.1; -; mRNA.
DR   EMBL; EU952414; ACG24532.1; -; mRNA.
DR   EMBL; BT065116; ACN30992.1; -; mRNA.
DR   PIR; T02242; T02242.
DR   RefSeq; NP_001106078.1; NM_001112608.1.
DR   AlphaFoldDB; P49103; -.
DR   SMR; P49103; -.
DR   STRING; 4577.GRMZM2G330430_P02; -.
DR   PaxDb; P49103; -.
DR   PRIDE; P49103; -.
DR   ProMEX; P49103; -.
DR   GeneID; 100127017; -.
DR   KEGG; zma:100127017; -.
DR   MaizeGDB; 121973; -.
DR   eggNOG; KOG0098; Eukaryota.
DR   HOGENOM; CLU_041217_23_1_1; -.
DR   OrthoDB; 1271975at2759; -.
DR   Proteomes; UP000007305; Unplaced.
DR   ExpressionAtlas; P49103; baseline and differential.
DR   Genevisible; P49103; ZM.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR   GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   Pfam; PF00071; Ras; 1.
DR   SMART; SM00174; RHO; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51419; RAB; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Golgi apparatus; GTP-binding; Lipoprotein; Membrane;
KW   Nucleotide-binding; Prenylation; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..209
FT                   /note="Ras-related protein Rab-2-A"
FT                   /id="PRO_0000121073"
FT   MOTIF           35..43
FT                   /note="Effector region"
FT                   /evidence="ECO:0000250"
FT   BINDING         13..21
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:P61019"
FT   BINDING         61..65
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:P62820"
FT   BINDING         119..122
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:P61019"
FT   BINDING         149..151
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250|UniProtKB:P61019"
FT   LIPID           207
FT                   /note="S-geranylgeranyl cysteine"
FT                   /evidence="ECO:0000250"
FT   LIPID           208
FT                   /note="S-geranylgeranyl cysteine"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        49
FT                   /note="T -> N (in Ref. 1; AAA63901)"
SQ   SEQUENCE   209 AA;  22988 MW;  431F20AC95C21CE0 CRC64;
     MSYAYLFKYI IIGDTGVGKS CLLLQFTDKR FQPVHDLTIG VEFGARMITI DNKPIKLQIW
     DTAGQESFRS ITRSYYRGAA GALLVYDITR RETFNHLASW LEDARQHANA NMTIMLVGNK
     CDLSHRRAVS YEEGEQFAKE HGLIFMEASA KTAQNVEEAF VKTAGAIYKK IQDGVFDVSN
     ESYGIKVGYV VPGQSGGAGS SSQGGGCCS