PRP4_ARATH
ID PRP4_ARATH Reviewed; 448 AA.
AC Q9T0I5; B9DHX5; Q9M6T6; Q9M7N8;
DT 03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 116.
DE RecName: Full=Proline-rich protein 4;
DE Short=AtPRP4;
DE Flags: Precursor;
GN Name=PRP4; OrderedLocusNames=At4g38770; ORFNames=T9A14.50;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], TISSUE SPECIFICITY, AND DEVELOPMENTAL
RP STAGE.
RC STRAIN=cv. Columbia, and cv. Landsberg erecta;
RX PubMed=10594096; DOI=10.1104/pp.121.4.1081;
RA Fowler T.J., Bernhardt C., Tierney M.L.;
RT "Characterization and expression of four proline-rich cell wall protein
RT genes in Arabidopsis encoding two distinct subsets of multiple domain
RT proteins.";
RL Plant Physiol. 121:1081-1092(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=10890533; DOI=10.1023/a:1006480107407;
RA Smart L.B., Cameron K.D., Bennett A.B.;
RT "Isolation of genes predominantly expressed in guard cells and epidermal
RT cells of Nicotiana glauca.";
RL Plant Mol. Biol. 42:857-869(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 172-448.
RC STRAIN=cv. Columbia; TISSUE=Flower, and Silique;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in aerial organs, particularly in
CC expanding leaves, stems, flowers, and siliques. Also present in
CC stipules. {ECO:0000269|PubMed:10594096}.
CC -!- DEVELOPMENTAL STAGE: In young seedlings, detected in the hypocotyl,
CC cotyledons and rosette leaves,mostly in expanding leaves. At flowering
CC time, expressed in stems, cauline leaves, sepals, and, in open flowers
CC only, in anthers and on stigma surface. Later present in pedicels of
CC developing siliques, nectaries, and along the length of maturing
CC siliques. Expressed in roots during the early stages of lateral root
CC formation. {ECO:0000269|PubMed:10594096}.
CC -!- SIMILARITY: Belongs to the plant proline-rich protein superfamily.
CC {ECO:0000305}.
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DR EMBL; AF110988; AAF64551.1; -; Genomic_DNA.
DR EMBL; AF151217; AAF28388.1; -; mRNA.
DR EMBL; AL035656; CAB38611.1; -; Genomic_DNA.
DR EMBL; AL161594; CAB80540.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE86972.1; -; Genomic_DNA.
DR EMBL; AY054212; AAL06873.1; -; mRNA.
DR EMBL; AY092992; AAM12991.1; -; mRNA.
DR EMBL; BT000944; AAN41344.1; -; mRNA.
DR EMBL; BT001204; AAN65091.1; -; mRNA.
DR EMBL; AY086263; AAM64336.1; -; mRNA.
DR EMBL; AK317683; BAH20342.1; -; mRNA.
DR PIR; T06076; T06076.
DR RefSeq; NP_195588.1; NM_120037.4.
DR AlphaFoldDB; Q9T0I5; -.
DR BioGRID; 15312; 1.
DR IntAct; Q9T0I5; 1.
DR STRING; 3702.AT4G38770.1; -.
DR PaxDb; Q9T0I5; -.
DR PRIDE; Q9T0I5; -.
DR ProteomicsDB; 226220; -.
DR EnsemblPlants; AT4G38770.1; AT4G38770.1; AT4G38770.
DR GeneID; 830032; -.
DR Gramene; AT4G38770.1; AT4G38770.1; AT4G38770.
DR KEGG; ath:AT4G38770; -.
DR Araport; AT4G38770; -.
DR TAIR; locus:2141777; AT4G38770.
DR eggNOG; ENOG502QTFH; Eukaryota.
DR HOGENOM; CLU_042219_1_0_1; -.
DR InParanoid; Q9T0I5; -.
DR OMA; KSFPPIY; -.
DR OrthoDB; 1452968at2759; -.
DR PRO; PR:Q9T0I5; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9T0I5; baseline and differential.
DR Genevisible; Q9T0I5; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
PE 2: Evidence at transcript level;
KW Cell wall; Reference proteome; Repeat; Secreted; Signal.
FT SIGNAL 1..29
FT /evidence="ECO:0000255"
FT CHAIN 30..448
FT /note="Proline-rich protein 4"
FT /id="PRO_0000419275"
FT REPEAT 152..156
FT /note="1"
FT REPEAT 157..161
FT /note="2"
FT REPEAT 165..169
FT /note="3"
FT REPEAT 170..174
FT /note="4"
FT REPEAT 175..179
FT /note="5"
FT REPEAT 183..187
FT /note="6"
FT REPEAT 188..193
FT /note="7"
FT REPEAT 194..198
FT /note="8"
FT REPEAT 201..205
FT /note="9"
FT REPEAT 208..212
FT /note="10"
FT REPEAT 216..220
FT /note="11"
FT REPEAT 222..226
FT /note="12"
FT REPEAT 227..231
FT /note="13"
FT REPEAT 232..236
FT /note="14"
FT REPEAT 238..242
FT /note="15"
FT REPEAT 245..249
FT /note="16"
FT REPEAT 250..254
FT /note="17"
FT REPEAT 256..259
FT /note="18"
FT REPEAT 260..264
FT /note="19"
FT REPEAT 265..270
FT /note="20"
FT REPEAT 271..278
FT /note="21"
FT REPEAT 279..284
FT /note="22"
FT REPEAT 286..294
FT /note="23"
FT REPEAT 295..299
FT /note="24"
FT REPEAT 300..304
FT /note="25"
FT REPEAT 306..311
FT /note="26"
FT REPEAT 314..320
FT /note="27"
FT REPEAT 321..327
FT /note="28"
FT REPEAT 328..334
FT /note="29"
FT REPEAT 335..341
FT /note="30"
FT REPEAT 342..348
FT /note="31"
FT REPEAT 349..356
FT /note="32"
FT REPEAT 357..363
FT /note="33"
FT REPEAT 364..368
FT /note="34"
FT REPEAT 369..374
FT /note="35"
FT REPEAT 378..384
FT /note="36"
FT REPEAT 385..389
FT /note="37"
FT REPEAT 390..394
FT /note="38"
FT REPEAT 395..402
FT /note="39"
FT REPEAT 403..407
FT /note="40"
FT REPEAT 409..413
FT /note="41"
FT REPEAT 414..419
FT /note="42"
FT REPEAT 420..424
FT /note="43"
FT REPEAT 425..429
FT /note="44"
FT REPEAT 430..434
FT /note="45"
FT REPEAT 442..446
FT /note="46"
FT REGION 152..446
FT /note="46 X 5 AA approximate repeats"
FT REGION 240..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 262
FT /note="Y -> F (in Ref. 2; AAF28388 and 6; AAM64336)"
FT /evidence="ECO:0000305"
FT CONFLICT 270
FT /note="K -> H (in Ref. 1; AAF64551, 2; AAF28388 and 6;
FT AAM64336)"
FT /evidence="ECO:0000305"
FT CONFLICT 294
FT /note="L -> P (in Ref. 1; AAF64551, 2; AAF28388 and 6;
FT AAM64336)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 448 AA; 49136 MW; 5931DC9BEAF749B8 CRC64;
MRILPEPRGS VPCLLLLVSV LLSATLSLAR VVEVVGYAES KIKTPHAFSG LRVTIDCKVN
KGHFVTKGSG NIDDKGKFGL NIPHDIVSDN GALKEECYAQ LHSAAGTPCP AHDGLESTKI
VFLSKSGDKH ILGLKQNLKF SPEICVSKFF WPMPKLPPFK GFDHPFPLPP PLELPPFLKK
PCPPKYSPPV EVPPPVPVYE PPPKKEIPPP VPVYDPPPKK EVPPPVPVYK PPPKVELPPP
IPKKPCPPKP PKIEHPPPVP VYKPPPKIEK PPPVPVYKPP PKIEHPPPVP VHKLPKKPCP
PKKVDPPPVP VHKPPTKKPC PPKKVDPPPV PVHKPPPKIV IPPPKIEHPP PVPVYKPPPK
IEHPPIYIPP IVKKPCPPPV PIYKPPVVIP KKPCPPPVPV YKPPVVVIPK KPCPPLPQLP
PLPKFPPLPP KYIHHPKFGK WPPLPPHP
