PROQ_YERPE
ID PROQ_YERPE Reviewed; 237 AA.
AC Q8ZFJ9; Q0WG81;
DT 02-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=RNA chaperone ProQ {ECO:0000255|HAMAP-Rule:MF_00749};
GN Name=proQ {ECO:0000255|HAMAP-Rule:MF_00749};
GN OrderedLocusNames=YPO1704, y1866, YP_1729;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- FUNCTION: RNA chaperone with significant RNA binding, RNA strand
CC exchange and RNA duplexing activities. May regulate ProP activity
CC through an RNA-based, post-transcriptional mechanism.
CC {ECO:0000255|HAMAP-Rule:MF_00749}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00749}.
CC -!- SIMILARITY: Belongs to the ProQ family. {ECO:0000255|HAMAP-
CC Rule:MF_00749}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL590842; CAL20347.1; -; Genomic_DNA.
DR EMBL; AE009952; AAM85433.1; -; Genomic_DNA.
DR EMBL; AE017042; AAS61957.1; -; Genomic_DNA.
DR PIR; AH0207; AH0207.
DR RefSeq; WP_002210849.1; NZ_WUCM01000041.1.
DR RefSeq; YP_002346707.1; NC_003143.1.
DR AlphaFoldDB; Q8ZFJ9; -.
DR SMR; Q8ZFJ9; -.
DR STRING; 214092.YPO1704; -.
DR PaxDb; Q8ZFJ9; -.
DR DNASU; 1146813; -.
DR EnsemblBacteria; AAM85433; AAM85433; y1866.
DR EnsemblBacteria; AAS61957; AAS61957; YP_1729.
DR GeneID; 66841191; -.
DR KEGG; ype:YPO1704; -.
DR KEGG; ypk:y1866; -.
DR KEGG; ypm:YP_1729; -.
DR PATRIC; fig|214092.21.peg.2055; -.
DR eggNOG; COG3109; Bacteria.
DR HOGENOM; CLU_113254_0_0_6; -.
DR OMA; WRYLKGV; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0033592; F:RNA strand annealing activity; IBA:GO_Central.
DR GO; GO:0034057; F:RNA strand-exchange activity; IBA:GO_Central.
DR GO; GO:0010608; P:post-transcriptional regulation of gene expression; IBA:GO_Central.
DR Gene3D; 1.10.1710.10; -; 1.
DR HAMAP; MF_00749; ProQ; 1.
DR InterPro; IPR023529; ProQ.
DR InterPro; IPR016103; ProQ/FinO.
DR InterPro; IPR036442; ProQ/FinO_sf.
DR InterPro; IPR035236; ProQ_C.
DR PANTHER; PTHR38106; PTHR38106; 2.
DR Pfam; PF04352; ProQ; 1.
DR Pfam; PF17516; ProQ_C; 1.
DR SMART; SM00945; ProQ; 1.
DR SUPFAM; SSF48657; SSF48657; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Reference proteome; RNA-binding.
FT CHAIN 1..237
FT /note="RNA chaperone ProQ"
FT /id="PRO_0000214629"
FT REGION 106..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..155
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..178
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 237 AA; 26498 MW; F64F645A778F188F CRC64;
MENQPKLNSS KEVIAFLAER FPLCFTAEGE ARPLKIGIFQ DLVERVQGEE NLSKTQLRSA
LRLYTSSWRY LYGVKVGAER VDLDGNPCGV LEEQHVEHAR KQLEEAKARV QAQRAEQQAK
KREAAIAAGE TPEPRRPRPA GKKPAPRREA GAAPENRKPR QSPRPQQVRP PRPQVEENQP
RPVPVTDISK LQIGQEIKVR AGKSAMDATV LEIAKDGVRV QLSSGLAMIV RAEHLQF
