ID   PROQ_VIBCH              Reviewed;         208 AA.
AC   Q9KRY6;
DT   02-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=RNA chaperone ProQ {ECO:0000255|HAMAP-Rule:MF_00749};
GN   Name=proQ {ECO:0000255|HAMAP-Rule:MF_00749}; OrderedLocusNames=VC_1497;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: RNA chaperone with significant RNA binding, RNA strand
CC       exchange and RNA duplexing activities. {ECO:0000255|HAMAP-
CC       Rule:MF_00749}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00749}.
CC   -!- SIMILARITY: Belongs to the ProQ family. {ECO:0000255|HAMAP-
CC       Rule:MF_00749}.
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DR   EMBL; AE003852; AAF94652.1; -; Genomic_DNA.
DR   PIR; D82192; D82192.
DR   RefSeq; NP_231138.1; NC_002505.1.
DR   RefSeq; WP_000432038.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9KRY6; -.
DR   SMR; Q9KRY6; -.
DR   STRING; 243277.VC_1497; -.
DR   DNASU; 2614003; -.
DR   EnsemblBacteria; AAF94652; AAF94652; VC_1497.
DR   GeneID; 57740157; -.
DR   KEGG; vch:VC_1497; -.
DR   PATRIC; fig|243277.26.peg.1424; -.
DR   eggNOG; COG3109; Bacteria.
DR   HOGENOM; CLU_113254_0_0_6; -.
DR   OMA; WRYLKGV; -.
DR   BioCyc; VCHO:VC1497-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0033592; F:RNA strand annealing activity; IBA:GO_Central.
DR   GO; GO:0034057; F:RNA strand-exchange activity; IBA:GO_Central.
DR   GO; GO:0010608; P:post-transcriptional regulation of gene expression; IBA:GO_Central.
DR   Gene3D; 1.10.1710.10; -; 1.
DR   HAMAP; MF_00749; ProQ; 1.
DR   InterPro; IPR023529; ProQ.
DR   InterPro; IPR016103; ProQ/FinO.
DR   InterPro; IPR036442; ProQ/FinO_sf.
DR   InterPro; IPR035236; ProQ_C.
DR   PANTHER; PTHR38106; PTHR38106; 1.
DR   Pfam; PF04352; ProQ; 1.
DR   Pfam; PF17516; ProQ_C; 1.
DR   SMART; SM00945; ProQ; 1.
DR   SUPFAM; SSF48657; SSF48657; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Reference proteome; RNA-binding.
FT   CHAIN           1..208
FT                   /note="RNA chaperone ProQ"
FT                   /id="PRO_0000214625"
FT   REGION          107..152
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        107..131
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   208 AA;  23185 MW;  3549910651A47F76 CRC64;
     MENTEKLKNS KEVIAYIAEC FPNCFTLEGE AKPLKIGIFQ DLADRLNDDP KVSKTQLRAA
     LRQYTSSWRY LHGVKPGATR VDLDGNPCGE LEEQHVEHAQ AALAESKARV EARRKEQVKK
     VREEAKANKP KAKKPQQARR PQNAPKVEKK PVETRALAAS ELNVGNQVNV NMGKGNMAAT
     IVEVNKEDVR VQLANGLQMV VKAEHLRA