ID   PK81J_PSEFD             Reviewed;         360 AA.
AC   M2YMT1;
DT   07-OCT-2020, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2013, sequence version 1.
DT   03-AUG-2022, entry version 29.
DE   RecName: Full=Transcriptional coactivator MYCFIDRAFT_190109 {ECO:0000303|PubMed:30735556};
DE   AltName: Full=PKS8-1 gene cluster protein MYCFIDRAFT_190109 {ECO:0000303|PubMed:30735556};
GN   ORFNames=MYCFIDRAFT_190109;
OS   Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease
OS   fungus) (Mycosphaerella fijiensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Pseudocercospora.
OX   NCBI_TaxID=383855;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIRAD86;
RX   PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA   Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA   Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA   LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA   Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA   Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA   Grigoriev I.V.;
RT   "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT   genomes of eighteen Dothideomycetes fungi.";
RL   PLoS Pathog. 8:E1003037-E1003037(2012).
RN   [2]
RP   IDENTIFICATION, AND FUNCTION.
RX   PubMed=27388157; DOI=10.1371/journal.pone.0158471;
RA   Noar R.D., Daub M.E.;
RT   "Bioinformatics prediction of polyketide synthase gene clusters from
RT   Mycosphaerella fijiensis.";
RL   PLoS ONE 11:e0158471-e0158471(2016).
RN   [3]
RP   FUNCTION, INDUCTION, AND PATHWAY.
RX   PubMed=30735556; DOI=10.1371/journal.pone.0212229;
RA   Noar R.D., Thomas E., Daub M.E.;
RT   "A novel polyketide synthase gene cluster in the plant pathogenic fungus
RT   Pseudocercospora fijiensis.";
RL   PLoS ONE 14:e0212229-e0212229(2019).
CC   -!- FUNCTION: Transcriptional coactivator; part of the gene cluster that
CC       mediates the biosynthesis of an emodin derivative that may be involved
CC       in black Sigatoka disease of banana (PubMed:30735556). With
CC       MYCFIDRAFT_198930, coregulates the production of the PKS8-1 cluster
CC       product (Probable). {ECO:0000269|PubMed:30735556,
CC       ECO:0000305|PubMed:30735556}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- INDUCTION: Expression is up-regulated during banana leaves infection.
CC       {ECO:0000269|PubMed:30735556}.
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DR   EMBL; KB446562; EME79050.1; -; Genomic_DNA.
DR   RefSeq; XP_007929877.1; XM_007931686.1.
DR   AlphaFoldDB; M2YMT1; -.
DR   SMR; M2YMT1; -.
DR   EnsemblFungi; EME79050; EME79050; MYCFIDRAFT_190109.
DR   GeneID; 19335126; -.
DR   KEGG; pfj:MYCFIDRAFT_190109; -.
DR   eggNOG; KOG3178; Eukaryota.
DR   HOGENOM; CLU_005533_11_0_1; -.
DR   OrthoDB; 817726at2759; -.
DR   Proteomes; UP000016932; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..360
FT                   /note="Transcriptional coactivator MYCFIDRAFT_190109"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_5004030338"
FT   DOMAIN          3..67
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00393"
FT   DNA_BIND        33..52
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00393"
SQ   SEQUENCE   360 AA;  39117 MW;  C608A875202F686B CRC64;
     MQGMALNQLL ACLKWLGEFQ VLACIPLKGS IHARDVADLT GVPETQLCRV VRLMATAGFL
     HEPRPGQIAH TVLSGAFVTD LSLLDAGMFL SETAAPVALH MATATERQSD LQASNSAYSV
     AFNTSQPFEA ACVERSRLHR QWSAYSRCAG DAEDKTVELF GQLNWRSLGS ATIVDSCAQS
     TDLVLELAKL YPSLHFVVQM NNAAAVQQEA CRRPESEDVK RRMKIQERMP SAPQTVKDAA
     VYILRLPATL RPSAVQILAE LRAHLGALRA NSSATLILAT PLLPEPGTLD PDSEARARVR
     DLARLQLTNE TDLELSELIE LVNGVHDSNG RFRVVSKLRS RDSAATAALG IKYQAVPTAP