ID   PFDB_PYRFU              Reviewed;         117 AA.
AC   Q8U3S3;
DT   13-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   13-AUG-2002, sequence version 2.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Prefoldin subunit beta {ECO:0000255|HAMAP-Rule:MF_00307};
DE   AltName: Full=GimC subunit beta {ECO:0000255|HAMAP-Rule:MF_00307};
GN   Name=pfdB {ECO:0000255|HAMAP-Rule:MF_00307}; OrderedLocusNames=PF0382;
OS   Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=186497;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX   PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA   Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA   DiRuggiero J., Robb F.T.;
RT   "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT   horikoshii inferred from complete genomic sequences.";
RL   Genetics 152:1299-1305(1999).
CC   -!- FUNCTION: Molecular chaperone capable of stabilizing a range of
CC       proteins. Seems to fulfill an ATP-independent, HSP70-like function in
CC       archaeal de novo protein folding. {ECO:0000255|HAMAP-Rule:MF_00307}.
CC   -!- SUBUNIT: Heterohexamer of two alpha and four beta subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00307}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00307}.
CC   -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC       {ECO:0000255|HAMAP-Rule:MF_00307}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAL80506.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE009950; AAL80506.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_014835119.1; NZ_CP023154.1.
DR   AlphaFoldDB; Q8U3S3; -.
DR   SMR; Q8U3S3; -.
DR   STRING; 186497.PF0382; -.
DR   EnsemblBacteria; AAL80506; AAL80506; PF0382.
DR   GeneID; 41712152; -.
DR   KEGG; pfu:PF0382; -.
DR   PATRIC; fig|186497.12.peg.397; -.
DR   eggNOG; arCOG01342; Archaea.
DR   HOGENOM; CLU_131909_1_1_2; -.
DR   OMA; PPQVQAM; -.
DR   OrthoDB; 116327at2157; -.
DR   PhylomeDB; Q8U3S3; -.
DR   Proteomes; UP000001013; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016272; C:prefoldin complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.287.370; -; 1.
DR   HAMAP; MF_00307; PfdB; 1.
DR   InterPro; IPR002777; PFD_beta-like.
DR   InterPro; IPR012713; PfdB.
DR   InterPro; IPR009053; Prefoldin.
DR   Pfam; PF01920; Prefoldin_2; 1.
DR   TIGRFAMs; TIGR02338; gimC_beta; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Reference proteome.
FT   CHAIN           1..117
FT                   /note="Prefoldin subunit beta"
FT                   /id="PRO_0000124866"
SQ   SEQUENCE   117 AA;  13332 MW;  5795F361BF26A1DD CRC64;
     MQNIPPQVQA MLGQLESYQQ QLQLVIQQKQ KVQADLNEAK KALEEIEKLT DDAVIYKTVG
     TLIVKTTKEK ALQELKEKVE TLEVRLNALN RQEQKINEKI KELTQKIQAA LRPPTAG