ID   PFDB_PYRAE              Reviewed;         126 AA.
AC   Q8ZVN4;
DT   13-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Prefoldin subunit beta;
DE   AltName: Full=GimC subunit beta;
GN   Name=pfdB; OrderedLocusNames=PAE2199;
OS   Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP
OS   104966 / NBRC 100827 / IM2).
OC   Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Pyrobaculum.
OX   NCBI_TaxID=178306;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2;
RX   PubMed=11792869; DOI=10.1073/pnas.241636498;
RA   Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I.,
RA   Miller J.H.;
RT   "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum
RT   aerophilum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002).
CC   -!- FUNCTION: Molecular chaperone capable of stabilizing a range of
CC       proteins. Seems to fulfill an ATP-independent, HSP70-like function in
CC       archaeal de novo protein folding (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Heterohexamer of two alpha and four beta subunits.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC       {ECO:0000305}.
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DR   EMBL; AE009441; AAL64022.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8ZVN4; -.
DR   SMR; Q8ZVN4; -.
DR   STRING; 178306.PAE2199; -.
DR   EnsemblBacteria; AAL64022; AAL64022; PAE2199.
DR   KEGG; pai:PAE2199; -.
DR   PATRIC; fig|178306.9.peg.1633; -.
DR   eggNOG; arCOG01342; Archaea.
DR   HOGENOM; CLU_131909_2_1_2; -.
DR   InParanoid; Q8ZVN4; -.
DR   OMA; PPQVQAM; -.
DR   Proteomes; UP000002439; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016272; C:prefoldin complex; IBA:GO_Central.
DR   GO; GO:0051087; F:chaperone binding; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; IBA:GO_Central.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   Gene3D; 1.10.287.370; -; 1.
DR   HAMAP; MF_00307; PfdB; 1.
DR   InterPro; IPR002777; PFD_beta-like.
DR   InterPro; IPR012713; PfdB.
DR   InterPro; IPR009053; Prefoldin.
DR   Pfam; PF01920; Prefoldin_2; 1.
DR   TIGRFAMs; TIGR02338; gimC_beta; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Reference proteome.
FT   CHAIN           1..126
FT                   /note="Prefoldin subunit beta"
FT                   /id="PRO_0000124865"
SQ   SEQUENCE   126 AA;  14403 MW;  20693D4682E094DD CRC64;
     MAQIPPSLQD LVNRFNQAQA QLQNVLLRKQ QYEAELKEVE KAISEIERLP QDAKIFKNVG
     NFLVPQSRDV ALQELRDRKE LLELHVKTLT RQESMLREQL DKLREEINKE LAKLKGGATE
     AAKGGG