ID   PESC_MAGO7              Reviewed;         680 AA.
AC   A4RLI4; G4MWW8;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Pescadillo homolog {ECO:0000255|HAMAP-Rule:MF_03028};
DE   AltName: Full=Nucleolar protein 7 homolog {ECO:0000255|HAMAP-Rule:MF_03028};
GN   Name=NOP7 {ECO:0000255|HAMAP-Rule:MF_03028}; ORFNames=MGG_01183;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: Component of the NOP7 complex, which is required for
CC       maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S
CC       ribosome. {ECO:0000255|HAMAP-Rule:MF_03028}.
CC   -!- SUBUNIT: Component of the NOP7 complex, composed of ERB1, NOP7 and
CC       YTM1. The complex is held together by ERB1, which interacts with NOP7
CC       via its N-terminal domain and with YTM1 via a high-affinity interaction
CC       between the seven-bladed beta-propeller domains of the 2 proteins. The
CC       NOP7 complex associates with the 66S pre-ribosome. {ECO:0000255|HAMAP-
CC       Rule:MF_03028}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000255|HAMAP-
CC       Rule:MF_03028}. Nucleus, nucleoplasm {ECO:0000255|HAMAP-Rule:MF_03028}.
CC   -!- SIMILARITY: Belongs to the pescadillo family. {ECO:0000255|HAMAP-
CC       Rule:MF_03028}.
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DR   EMBL; CM001232; EHA54260.1; -; Genomic_DNA.
DR   RefSeq; XP_003714067.1; XM_003714019.1.
DR   AlphaFoldDB; A4RLI4; -.
DR   SMR; A4RLI4; -.
DR   STRING; 318829.MGG_01183T0; -.
DR   EnsemblFungi; MGG_01183T0; MGG_01183T0; MGG_01183.
DR   GeneID; 2679784; -.
DR   KEGG; mgr:MGG_01183; -.
DR   VEuPathDB; FungiDB:MGG_01183; -.
DR   eggNOG; KOG2481; Eukaryota.
DR   HOGENOM; CLU_019619_1_1_1; -.
DR   InParanoid; A4RLI4; -.
DR   OMA; TWIVPHY; -.
DR   OrthoDB; 777920at2759; -.
DR   Proteomes; UP000009058; Chromosome 2.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-UniRule.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.10190; -; 1.
DR   HAMAP; MF_03028; Pescadillo; 1.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR010613; PES.
DR   PANTHER; PTHR12221; PTHR12221; 1.
DR   Pfam; PF00533; BRCT; 1.
DR   Pfam; PF06732; Pescadillo_N; 1.
DR   SMART; SM00292; BRCT; 1.
DR   SUPFAM; SSF52113; SSF52113; 1.
DR   PROSITE; PS50172; BRCT; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..680
FT                   /note="Pescadillo homolog"
FT                   /id="PRO_0000370495"
FT   DOMAIN          359..471
FT                   /note="BRCT"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_03028"
FT   REGION          315..336
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          494..680
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          609..680
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_03028"
FT   COMPBIAS        508..559
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        593..668
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   680 AA;  75961 MW;  79BA2B08DCCCCBE6 CRC64;
     MGRIKKKGES GAAKNYITRT QAVRKLQISL PDFRKLCIWK GIYPREPRNK KKVSKSATAS
     TTFYYTKDIQ YLLHEPLLAK FRDQKVLEKK ISRALGRGDV SDAKRLEGNA ARPENTGKPS
     YTLDHVVRER YPTFVDALRD LDDCLSMLFL FANLPATSSV PAKMIARCER LCLEFQHYLI
     VSHSLQKSFL SIKGIYYQAN IQGEDILWLV PYKFNQRVVG DIDFRIMGTF IEFYMTLLGF
     VNFRLYTSIG LKYPPKFDAT KDDKAADLAA FTLEGAGLTS NGAQPDAIME GTSESTPDPK
     LQAKVNKLVK ELKSGEDEKP KAITNGEGES ETPTDAIDKF EPAAPGGDVL LQPSYSTSDP
     SQLFANCTIY LSREAPRQAL EFILRAFGCK RIGWDEVLGD GAFTTNELDP NITHQIVDRP
     PVTAVDNDEG EDNQTAQKVG GRVPGRIYVQ PQWVWDSIND EELKEPNQYA PGAQLPPHLS
     PFVKARAGQY DPTVPLEEQQ TEAEALKGDS DVEDEEEADG AEADEDDDEA VLAIENGEMD
     VAGSDDDDDE EDEEADAGFG GFSDAEVDDA SEDDEQTSAA LQRQIELEAE LSGKSVKASE
     ADKQAADPKS KAKQQKRKEL QRKAKEEAED LERAKGMLSK KKRKLFEQMT YSNNKKDAES
     EKLREKRRRI ERKMAKGKAT