PESC_CHLRE
ID PESC_CHLRE Reviewed; 678 AA.
AC A8JBB2;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 1.
DT 25-MAY-2022, entry version 67.
DE RecName: Full=Pescadillo homolog {ECO:0000255|HAMAP-Rule:MF_03028};
GN ORFNames=CHLREDRAFT_206018;
OS Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX NCBI_TaxID=3055;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-503;
RX PubMed=17932292; DOI=10.1126/science.1143609;
RA Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.J.,
RA Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT "The Chlamydomonas genome reveals the evolution of key animal and plant
RT functions.";
RL Science 318:245-250(2007).
CC -!- FUNCTION: Required for maturation of ribosomal RNAs and formation of
CC the large ribosomal subunit. {ECO:0000255|HAMAP-Rule:MF_03028}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000255|HAMAP-
CC Rule:MF_03028}. Nucleus, nucleoplasm {ECO:0000255|HAMAP-Rule:MF_03028}.
CC -!- SIMILARITY: Belongs to the pescadillo family. {ECO:0000255|HAMAP-
CC Rule:MF_03028}.
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DR EMBL; DS496152; EDO98904.1; -; Genomic_DNA.
DR RefSeq; XP_001699264.1; XM_001699212.1.
DR AlphaFoldDB; A8JBB2; -.
DR SMR; A8JBB2; -.
DR STRING; 3055.EDO98904; -.
DR PaxDb; A8JBB2; -.
DR ProMEX; A8JBB2; -.
DR GeneID; 5724754; -.
DR eggNOG; KOG2481; Eukaryota.
DR HOGENOM; CLU_019619_1_0_1; -.
DR InParanoid; A8JBB2; -.
DR OrthoDB; 777920at2759; -.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-UniRule.
DR GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.10190; -; 1.
DR HAMAP; MF_03028; Pescadillo; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR010613; PES.
DR PANTHER; PTHR12221; PTHR12221; 1.
DR Pfam; PF06732; Pescadillo_N; 1.
DR SUPFAM; SSF52113; SSF52113; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..678
FT /note="Pescadillo homolog"
FT /id="PRO_0000370475"
FT DOMAIN 361..451
FT /note="BRCT"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03028"
FT REGION 283..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 552..587
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03028"
FT COMPBIAS 283..303
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..579
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 678 AA; 73862 MW; 18BB619F84FC7400 CRC64;
MAGKKLKKGK SGNAAQYITR TQAVRKLQLR LSEFRRLCIL KGVHPREPKK KPKGANKTYY
HLKDINWLAH EPLLNTFRSI KAHDKKVRKA RAKQNKELAK RLAALTPTYR LDHLVKERYP
SFVDALRDLD DSLTMVHLFA TLPAESKYDI PQRTVQLCRR LALEWQAYVV RSGALRRVFV
SVKGYYFQAE ILGQSVTWLV PHALSQVLPP DVDYKVMLTF LEFYNTLLQF VNFKLYHNLG
AALPSLRVYP LFSQLRYPPV LDPRLEEAAA ELAAIMKDIA GMEEEEPEEV DSEAGDEDDD
DLPVLDSGTR RRRAAAAGPA PRRWRCWVRT TRTRMTTCRW VSDRAGGACG PGVDPSDEAA
VCGSLFRGRV FFLGREVPRE PLMLVIRAFG GVAAWDGDGS PHAETDEAVT HQIVDRPKQG
HKFLSREYVQ PQWVFDSANF RVLMPTDLYA PGTVPPPHLS PFVGEADEDG YTPDFAKTVR
RLQDAANAAR LRAAGLALKG ADGSEFVGEG ADGAAAADGE GAAGEDLAAA ERQYASELAK
EDEEAAMADI MMTRKARKMY NNMKQKEAAK QERVQQLESK KAKLAATGAA GPMGQVKPAA
AGKAAAAKAA APAKVAASGG KGAAAKGKEA PAPAKGKGTP AAKGKEAPAP AKGKGAAAAK
EAPAKGGKDA APAKRQRR
