PCP10_ARATH
ID PCP10_ARATH Reviewed; 132 AA.
AC Q9SKW7;
DT 10-MAY-2017, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2017, sequence version 2.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Precursor of CEP10 {ECO:0000303|PubMed:24179096};
DE Short=PCEP10 {ECO:0000303|PubMed:24179096};
DE Contains:
DE RecName: Full=C-terminally encoded peptide 10.1 {ECO:0000303|PubMed:24179096};
DE Short=CEP10.1 {ECO:0000303|PubMed:24179096};
DE Contains:
DE RecName: Full=C-terminally encoded peptide 10.2 {ECO:0000303|PubMed:24179096};
DE Short=CEP10.2 {ECO:0000303|PubMed:24179096};
DE Contains:
DE RecName: Full=C-terminally encoded peptide 10.3 {ECO:0000303|PubMed:24179096};
DE Short=CEP10.3 {ECO:0000303|PubMed:24179096};
DE Flags: Precursor;
GN Name=CEP10 {ECO:0000303|PubMed:24179096};
GN OrderedLocusNames=At1g36045 {ECO:0000305};
GN ORFNames=F5J5.3 {ECO:0000312|EMBL:AAF18632.1}, T22A15 {ECO:0000305};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RC STRAIN=cv. Columbia;
RX PubMed=24179095; DOI=10.1093/jxb/ert331;
RA Roberts I., Smith S., De Rybel B., Van Den Broeke J., Smet W.,
RA De Cokere S., Mispelaere M., De Smet I., Beeckman T.;
RT "The CEP family in land plants: evolutionary analyses, expression studies,
RT and role in Arabidopsis shoot development.";
RL J. Exp. Bot. 64:5371-5381(2013).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=24179096; DOI=10.1093/jxb/ert332;
RA Delay C., Imin N., Djordjevic M.A.;
RT "CEP genes regulate root and shoot development in response to environmental
RT cues and are specific to seed plants.";
RL J. Exp. Bot. 64:5383-5394(2013).
CC -!- FUNCTION: Extracellular signaling peptide that may regulate primary
CC root growth rate and systemic nitrogen (N)-demand signaling.
CC {ECO:0000250|UniProtKB:Q8L8Y3}.
CC -!- SUBUNIT: Interacts with CEP receptors (e.g. CEPR1 and CEPR2).
CC {ECO:0000250|UniProtKB:Q8L8Y3}.
CC -!- SUBCELLULAR LOCATION: [C-terminally encoded peptide 10.1]: Secreted,
CC extracellular space, apoplast {ECO:0000250|UniProtKB:O80460}.
CC Note=Accumulates in xylem sap. {ECO:0000250|UniProtKB:O80460}.
CC -!- SUBCELLULAR LOCATION: [C-terminally encoded peptide 10.2]: Secreted,
CC extracellular space, apoplast {ECO:0000250|UniProtKB:O80460}.
CC Note=Accumulates in xylem sap. {ECO:0000250|UniProtKB:O80460}.
CC -!- SUBCELLULAR LOCATION: [C-terminally encoded peptide 10.3]: Secreted,
CC extracellular space, apoplast {ECO:0000250|UniProtKB:O80460}.
CC Note=Accumulates in xylem sap. {ECO:0000250|UniProtKB:O80460}.
CC -!- PTM: The mature small signaling peptide is generated by proteolytic
CC processing of the longer precursor. {ECO:0000250|UniProtKB:Q8L8Y3}.
CC -!- SIMILARITY: Belongs to the C-terminally encoded plant signaling peptide
CC (CEP) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF18632.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC006228; AAF18632.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC021666; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; D86482; D86482.
DR AlphaFoldDB; Q9SKW7; -.
DR PRIDE; Q9SKW7; -.
DR Araport; AT1G36045; -.
DR PRO; PR:Q9SKW7; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SKW7; baseline.
DR GO; GO:0048046; C:apoplast; ISS:UniProtKB.
DR GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR GO; GO:0005179; F:hormone activity; ISS:UniProtKB.
DR GO; GO:1902025; P:nitrate import; ISS:UniProtKB.
DR GO; GO:1901371; P:regulation of leaf morphogenesis; IBA:GO_Central.
DR GO; GO:2000280; P:regulation of root development; ISS:UniProtKB.
DR GO; GO:0048364; P:root development; IEA:InterPro.
DR InterPro; IPR033250; CEP.
DR PANTHER; PTHR33348; PTHR33348; 4.
PE 3: Inferred from homology;
KW Apoplast; Developmental protein; Hormone; Hydroxylation;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT PROPEP 20..66
FT /evidence="ECO:0000305"
FT /id="PRO_0000439997"
FT PEPTIDE 67..81
FT /note="C-terminally encoded peptide 10.1"
FT /evidence="ECO:0000250|UniProtKB:Q058G9"
FT /id="PRO_0000439998"
FT PROPEP 82..91
FT /evidence="ECO:0000305"
FT /id="PRO_0000439999"
FT PEPTIDE 92..106
FT /note="C-terminally encoded peptide 10.2"
FT /evidence="ECO:0000250|UniProtKB:Q058G9"
FT /id="PRO_0000440000"
FT PROPEP 107..116
FT /evidence="ECO:0000305"
FT /id="PRO_0000440001"
FT PEPTIDE 117..131
FT /note="C-terminally encoded peptide 10.3"
FT /evidence="ECO:0000250|UniProtKB:Q058G9"
FT /id="PRO_0000440002"
FT PROPEP 132
FT /evidence="ECO:0000305"
FT /id="PRO_0000440003"
FT MOD_RES 70
FT /note="Hydroxyproline"
FT /evidence="ECO:0000250|UniProtKB:Q8L8Y3"
FT MOD_RES 73
FT /note="Hydroxyproline"
FT /evidence="ECO:0000250|UniProtKB:Q058G9"
FT MOD_RES 95
FT /note="Hydroxyproline"
FT /evidence="ECO:0000250|UniProtKB:Q8L8Y3"
FT MOD_RES 98
FT /note="Hydroxyproline"
FT /evidence="ECO:0000250|UniProtKB:Q058G9"
FT MOD_RES 102
FT /note="Hydroxyproline"
FT /evidence="ECO:0000250|UniProtKB:Q8L8Y3"
FT MOD_RES 120
FT /note="Hydroxyproline"
FT /evidence="ECO:0000250|UniProtKB:Q8L8Y3"
FT MOD_RES 123
FT /note="Hydroxyproline"
FT /evidence="ECO:0000250|UniProtKB:Q058G9"
FT MOD_RES 127
FT /note="Hydroxyproline"
FT /evidence="ECO:0000250|UniProtKB:Q8L8Y3"
SQ SEQUENCE 132 AA; 14794 MW; 5E26618FC90BA025 CRC64;
MKLFIIIVVT SLTISKVFDK TLVTIEARNL RKMDRHEHFN ANEDFVEAKM LKKIDNKNNL
NNRCINDFAP TNPGHNSGIG HPKVINNKFT KDFAPTNPGH SPGIGHLRVV NNKFTNDFAP
TNPGNSPGIR HP
