ID   ASA1_KOMPG              Reviewed;         434 AA.
AC   C4R970;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=ASA1; OrderedLocusNames=PAS_chr4_0875;
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864;
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR   EMBL; FN392322; CAY72145.1; -; Genomic_DNA.
DR   RefSeq; XP_002494324.1; XM_002494279.1.
DR   AlphaFoldDB; C4R970; -.
DR   STRING; 644223.C4R970; -.
DR   EnsemblFungi; CAY72145; CAY72145; PAS_chr4_0875.
DR   GeneID; 8201273; -.
DR   KEGG; ppa:PAS_chr4_0875; -.
DR   eggNOG; KOG0322; Eukaryota.
DR   HOGENOM; CLU_045414_0_0_1; -.
DR   InParanoid; C4R970; -.
DR   OMA; WHNSENG; -.
DR   Proteomes; UP000000314; Chromosome 4.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..434
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402218"
FT   REPEAT          17..68
FT                   /note="WD 1"
FT   REPEAT          74..123
FT                   /note="WD 2"
SQ   SEQUENCE   434 AA;  48881 MW;  F3385D70F18CE5F3 CRC64;
     MHTHTSHGIE SDAMLRFHKS PVSALEPFYL PSPFVVNGEP LLLASLVSAD ENGWVVWWDL
     GTKRPLGTWR AHESTIVTVQ QMGIHWDADV PQLHRNTFGK LLTHGRDNCV RIWDLFRVSS
     FSSMDWNLCK VLHKTRDTAR NPDVYEIPVN ALNFCNVATR AEMIATPASL SSESFDIYVV
     SNHRLERLHS NVDICQILQQ NQRSNETDEN RKFGAIMQIT WTGDFQLAVG YESGIVACIQ
     LQERHTQVVW IDSSHLTHPI LGIVSNLDRV FTCSASDRIV VNSLQTGKTV AISKIKHKGI
     SSLDVTINNS ICLVSVTTWD GFSRIYRYDE DSSAAVDEAL KGVFIPWTKL RRIPPKVIPN
     FKSSSNHQTI DLPDLKGRVI KLSKTQNGCN NALVERSDGQ SKMILRSSEK RALTRYAFVG
     YQDGRVATYI LCDS