ID   ASA1_CANAW              Reviewed;         377 AA.
AC   C4YSJ2;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=ASA1; ORFNames=CAWG_05058;
OS   Candida albicans (strain WO-1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294748;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WO-1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR   EMBL; CM000312; EEQ46695.1; -; Genomic_DNA.
DR   AlphaFoldDB; C4YSJ2; -.
DR   SMR; C4YSJ2; -.
DR   STRING; 5476.C4YSJ2; -.
DR   EnsemblFungi; EEQ46695; EEQ46695; CAWG_05058.
DR   VEuPathDB; FungiDB:CAWG_05058; -.
DR   HOGENOM; CLU_045414_0_0_1; -.
DR   OMA; LVCCNTQ; -.
DR   Proteomes; UP000001429; Chromosome 6.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SMART; SM00320; WD40; 3.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Repeat; WD repeat.
FT   CHAIN           1..377
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402205"
FT   REPEAT          10..50
FT                   /note="WD 1"
FT   REPEAT          53..91
FT                   /note="WD 2"
FT   REPEAT          230..262
FT                   /note="WD 3"
FT   REPEAT          263..303
FT                   /note="WD 4"
FT   REPEAT          342..377
FT                   /note="WD 5"
SQ   SEQUENCE   377 AA;  42551 MW;  58A321EBAF24F267 CRC64;
     MLSTKFTLRS HKSSVTYIYQ DPRTPFNLFT ADSSGLIINW DLTIRRPKKS WQAHTDTILT
     ISTIHNHLLT HSRDNTIKIW DESYSCILEI PCNALNFSNI CVINDLLITP ASINSNNLDV
     YKIDKDWQIT RLIFDFDVYK LVNKGEIIEE IGSSGTSRND FGIIMQMKII HTNTTTTTSE
     NNSDYIIYVG FESGDIVGLQ LILPRARILS TTGNTNDKTL INQSAKFILQ YHNSTHVPNP
     VICLSNLDSV LVSGSTTNKV IIHSDPIEIM KMDHSGIQAI VNFKNDRLIF GYWNGYIQYG
     DISINQSLPK LGNTEQEKSK LTKKLTFMTI LNESNQETLQ SPTGKSKYSV LLKSKRNLVS
     PLLLAGYEDG SILAYNI