ID   ASA1_ASPNC              Reviewed;         440 AA.
AC   A2RA56;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=asa1; ORFNames=An18g01990;
OS   Aspergillus niger (strain CBS 513.88 / FGSC A1513).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=425011;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892;
RX   PubMed=17259976; DOI=10.1038/nbt1282;
RA   Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA   Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA   Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X.,
RA   Contreras R., Cornell M., Coutinho P.M., Danchin E.G.J., Debets A.J.M.,
RA   Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M.,
RA   d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J.,
RA   Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W.,
RA   van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M.,
RA   Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA   van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A.,
RA   Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E.,
RA   Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J.,
RA   Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H.,
RA   Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.;
RT   "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT   niger CBS 513.88.";
RL   Nat. Biotechnol. 25:221-231(2007).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR   EMBL; AM270398; CAK47271.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2RA56; -.
DR   PaxDb; A2RA56; -.
DR   EnsemblFungi; CAK47271; CAK47271; An18g01990.
DR   VEuPathDB; FungiDB:An18g01990; -.
DR   HOGENOM; CLU_041940_0_1_1; -.
DR   Proteomes; UP000006706; Chromosome 8L.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 3.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..440
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402203"
FT   REPEAT          21..60
FT                   /note="WD 1"
FT   REPEAT          66..107
FT                   /note="WD 2"
FT   REPEAT          205..245
FT                   /note="WD 3"
FT   REPEAT          264..303
FT                   /note="WD 4"
FT   REPEAT          315..354
FT                   /note="WD 5"
FT   REPEAT          406..440
FT                   /note="WD 6"
SQ   SEQUENCE   440 AA;  48497 MW;  9F841B1E4C38CA6D CRC64;
     MSAQSPQVRQ PPATPTYILR GHAAAIHALQ IFHQNLRLVS GDADGWIVVW DLVSKRPRAT
     WKAHDGTVLE VKGFSFGNGA VTEVFTHGRD HKLRVWRFSL QDEESLQKVL PVDIEKTSST
     AASQPWLVHS LPVNALNFCA FSMVFLPPDK ANTASDASEA PKENTSLSSV LIAVPNALNS
     GAIDLFHLPQ ERRICTIPAD TEVQTGMVMA ANLVISPSGE LYVASAYEDG RVMVHGCRGS
     LQEKDLTQST KTPWKWEKLY VCRAHSQPVL SLHVSPAGNY FFSSSADAVL AKHPIPSLGS
     PGHAPEELPI RSINTKHAGQ QGVRIRSDGK IFATAGWDSR VRVYSCKTMK ELAVLKWHKD
     GCYAVAFADV DVFEVREKSD EEKPTVSPND NGNQENQLAG RAETEFSLAT VHRQRYEKVQ
     NTHWLAAGSK DGKISLWDIY