OLF9_MOUSE
ID OLF9_MOUSE Reviewed; 312 AA.
AC Q60885; Q8VGC0;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 2.
DT 03-AUG-2022, entry version 148.
DE RecName: Full=Olfactory receptor 9;
DE AltName: Full=Odorant receptor M25;
DE AltName: Full=Olfactory receptor 269-3;
GN Name=Olfr9; Synonyms=Mor269-3;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11802173; DOI=10.1038/nn800;
RA Zhang X., Firestein S.;
RT "The olfactory receptor gene superfamily of the mouse.";
RL Nat. Neurosci. 5:124-133(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RT "Different evolutionary processes shaped the mouse and human olfactory
RT receptor gene families.";
RL Hum. Mol. Genet. 11:535-546(2002).
RN [3]
RP ERRATUM OF PUBMED:11875048.
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RL Hum. Mol. Genet. 11:1683-1683(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 128-239.
RC STRAIN=C57BL/6J;
RX PubMed=8570653; DOI=10.1073/pnas.93.2.884;
RA Sullivan S.L., Adamson M.C., Ressler K.J., Kozak C.A., Buck L.B.;
RT "The chromosomal distribution of mouse odorant receptor genes.";
RL Proc. Natl. Acad. Sci. U.S.A. 93:884-888(1996).
CC -!- FUNCTION: Odorant receptor. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AY073230; AAL60893.1; -; Genomic_DNA.
DR EMBL; AY317937; AAP71262.1; -; Genomic_DNA.
DR EMBL; U28774; AAC52397.1; -; Genomic_DNA.
DR CCDS; CCDS24302.1; -.
DR RefSeq; NP_667072.1; NM_146861.1.
DR AlphaFoldDB; Q60885; -.
DR SMR; Q60885; -.
DR STRING; 10090.ENSMUSP00000089622; -.
DR GlyGen; Q60885; 1 site.
DR PaxDb; Q60885; -.
DR PRIDE; Q60885; -.
DR Ensembl; ENSMUST00000091996; ENSMUSP00000089622; ENSMUSG00000069430.
DR GeneID; 18373; -.
DR KEGG; mmu:18373; -.
DR UCSC; uc007hpf.1; mouse.
DR CTD; 18373; -.
DR MGI; MGI:107600; Olfr9.
DR VEuPathDB; HostDB:ENSMUSG00000069430; -.
DR eggNOG; ENOG502SIWR; Eukaryota.
DR GeneTree; ENSGT01050000244815; -.
DR HOGENOM; CLU_012526_1_0_1; -.
DR InParanoid; Q60885; -.
DR OMA; ANANQDM; -.
DR OrthoDB; 982734at2759; -.
DR PhylomeDB; Q60885; -.
DR TreeFam; TF337350; -.
DR BioGRID-ORCS; 18373; 2 hits in 62 CRISPR screens.
DR PRO; PR:Q60885; -.
DR Proteomes; UP000000589; Chromosome 10.
DR RNAct; Q60885; protein.
DR ExpressionAtlas; Q60885; differential.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; G-protein coupled receptor; Glycoprotein; Membrane;
KW Olfaction; Receptor; Reference proteome; Sensory transduction; Transducer;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..312
FT /note="Olfactory receptor 9"
FT /id="PRO_0000150808"
FT TOPO_DOM 1..26
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 27..47
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 48..57
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..78
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 79..89
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 90..110
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 111..143
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 144..164
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 165..205
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 206..226
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 227..236
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 237..257
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 258..271
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..292
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 293..312
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 5
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 312 AA; 34611 MW; 590190ABE768516D CRC64;
MGDDNDTDIT EFILLGFSGY GFLQGHLFWG VLCIYVVTLL GNSLIVLLTL ADSALHSPMY
FFLRHFSVVE ILYTTTIVPR MLADLRSSCP TIPLASCFTQ LYFFALFGIA ECCLLTAMAY
DRYAAICCPL HYTTLMSQGT YTGLVGASYL AGVISGTTHS IFIFTLPFRG AKTIHHFLCD
ILPVLRLATA STFWGEVGNL FVTITFIFVP FLLIVASYAC ILVTILGVAT SQGRQKLFST
CSSHLFVVIL FFGTATVAYM RPQADSFGNT DQILTLVYTV VTPMCNPFVY SLRNKEVTGA
MRRLMKRYLW GP
