ID   OLF3_CANLF              Reviewed;         317 AA.
AC   Q95156;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 126.
DE   RecName: Full=Olfactory receptor-like protein OLF3;
OS   Canis lupus familiaris (Dog) (Canis familiaris).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis.
OX   NCBI_TaxID=9615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8855279; DOI=10.1073/pnas.93.20.10897;
RA   Issel-Tarver L., Rine J.;
RT   "Organization and expression of canine olfactory receptor genes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 93:10897-10902(1996).
CC   -!- FUNCTION: Putative odorant or sperm cell receptor.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U53681; AAB37241.1; -; Genomic_DNA.
DR   RefSeq; NP_001017516.1; NM_001017516.1.
DR   AlphaFoldDB; Q95156; -.
DR   SMR; Q95156; -.
DR   STRING; 9612.ENSCAFP00000038051; -.
DR   PaxDb; Q95156; -.
DR   Ensembl; ENSCAFT00030013226; ENSCAFP00030011562; ENSCAFG00030007211.
DR   Ensembl; ENSCAFT00845024099; ENSCAFP00845018929; ENSCAFG00845013528.
DR   GeneID; 482727; -.
DR   CTD; 26211; -.
DR   VEuPathDB; HostDB:ENSCAFG00845013528; -.
DR   eggNOG; ENOG502SKV6; Eukaryota.
DR   GeneTree; ENSGT01050000244837; -.
DR   HOGENOM; CLU_012526_1_0_1; -.
DR   InParanoid; Q95156; -.
DR   OMA; VFLMTPF; -.
DR   OrthoDB; 874222at2759; -.
DR   TreeFam; TF337251; -.
DR   Proteomes; UP000002254; Chromosome 16.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; G-protein coupled receptor; Glycoprotein; Membrane;
KW   Olfaction; Receptor; Reference proteome; Sensory transduction; Transducer;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..317
FT                   /note="Olfactory receptor-like protein OLF3"
FT                   /id="PRO_0000150801"
FT   TOPO_DOM        1..25
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        26..49
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        50..57
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..79
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        80..100
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..120
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        121..139
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..158
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        159..196
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        197..219
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        220..236
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        237..260
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        261..272
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        273..292
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        293..317
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        5
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   317 AA;  35238 MW;  815151BB4B7DE79F CRC64;
     MGTGNQTWVR EFVLLGLSSD WDTEVSLFVL FLITYMVTVL GNFLIILLIR LDSRLHTPMY
     FFLTNLSLVD VSYATSIIPQ MLAHLLAAHK AIPFVSCAAQ LFFSLGLGGI EFVLLAVMAY
     DRYVAVCDPL RYSVIMHGGL CTRLAITSWV SGSMNSLMQT VITFQLPMCT NKYIDHISCE
     LLAVVRLACV DTSSNEIAIM VSSIVLLMTP FCLVLLSYIQ IISTILKIQS TEGRKKAFHT
     CASHLTVVVL CYGMAIFTYI QPRSSPSVLQ EKLISLFYSV LTPMLNPMIY SVRNKEVKGA
     WQKLLGQLTG ITSKLAT