ID   OEP37_PEA               Reviewed;         329 AA.
AC   Q4LDF9;
DT   22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   03-AUG-2022, entry version 33.
DE   RecName: Full=Outer envelope pore protein 37, chloroplastic;
DE   AltName: Full=Chloroplastic outer envelope pore protein of 37 kDa;
DE            Short=PsOEP37;
DE   Flags: Precursor;
GN   Name=OEP37;
OS   Pisum sativum (Garden pea).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; IRL clade; Fabeae; Pisum.
OX   NCBI_TaxID=3888;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Golf; TISSUE=Leaf;
RA   Stahl T.;
RL   Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   FUNCTION, AND SUBUNIT.
RX   PubMed=16624824; DOI=10.1074/jbc.m600700200;
RA   Goetze T.A., Philippar K., Ilkavets I., Soll J., Wagner R.;
RT   "OEP37 is a new member of the chloroplast outer membrane ion channels.";
RL   J. Biol. Chem. 281:17989-17998(2006).
CC   -!- FUNCTION: Voltage-dependent peptide-sensitive high conductance
CC       rectifying cation channel with a strong affinity for TIC32 that is
CC       imported into the chloroplast. Conductance is pH-dependent decreasing
CC       with decreasing pH values. {ECO:0000269|PubMed:16624824}.
CC   -!- SUBUNIT: Forms an hourglass-shaped multimeric complex.
CC       {ECO:0000269|PubMed:16624824}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast outer membrane
CC       {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the plastid outer envelope porin OEP37 (TC
CC       1.B.47) family. {ECO:0000305}.
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DR   EMBL; AJ243759; CAB50915.1; -; mRNA.
DR   AlphaFoldDB; Q4LDF9; -.
DR   TCDB; 1.B.47.1.1; the plastid outer envelope porin of 37 kda (oep37) family.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:EnsemblPlants.
DR   GO; GO:0031359; C:integral component of chloroplast outer membrane; ISS:UniProtKB.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0005216; F:ion channel activity; IDA:UniProtKB.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006812; P:cation transport; IDA:UniProtKB.
DR   InterPro; IPR038951; OEP37-like.
DR   PANTHER; PTHR35484; PTHR35484; 1.
PE   1: Evidence at protein level;
KW   Chloroplast; Ion transport; Membrane; Plastid; Plastid outer membrane;
KW   Porin; Transit peptide; Transmembrane; Transmembrane beta strand;
KW   Transport.
FT   TRANSIT         1..57
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           58..329
FT                   /note="Outer envelope pore protein 37, chloroplastic"
FT                   /id="PRO_0000415712"
FT   TOPO_DOM        58..60
FT                   /note="Cytoplasmic"
FT   TRANSMEM        61..70
FT                   /note="Beta stranded; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        71..87
FT                   /note="Chloroplast intermembrane"
FT   TRANSMEM        88..97
FT                   /note="Beta stranded; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        98..113
FT                   /note="Cytoplasmic"
FT   TRANSMEM        114..121
FT                   /note="Beta stranded; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        122..138
FT                   /note="Chloroplast intermembrane"
FT   TRANSMEM        139..148
FT                   /note="Beta stranded; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        149..154
FT                   /note="Cytoplasmic"
FT   TRANSMEM        155..163
FT                   /note="Beta stranded; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        164..205
FT                   /note="Chloroplast intermembrane"
FT   TRANSMEM        206..214
FT                   /note="Beta stranded; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        215..216
FT                   /note="Cytoplasmic"
FT   TRANSMEM        217..226
FT                   /note="Beta stranded; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        227
FT                   /note="Chloroplast intermembrane"
FT   TRANSMEM        228..236
FT                   /note="Beta stranded; Name=8"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        237..243
FT                   /note="Cytoplasmic"
FT   TRANSMEM        244..253
FT                   /note="Beta stranded; Name=9"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        254..255
FT                   /note="Chloroplast intermembrane"
FT   TRANSMEM        256..265
FT                   /note="Beta stranded; Name=10"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        266..272
FT                   /note="Cytoplasmic"
FT   TRANSMEM        273..282
FT                   /note="Beta stranded; Name=11"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        283..302
FT                   /note="Chloroplast intermembrane"
FT   TRANSMEM        303..312
FT                   /note="Beta stranded; Name=12"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        313..329
FT                   /note="Cytoplasmic"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   329 AA;  37362 MW;  1978EA04858CA41F CRC64;
     MDSATRNPNY SPEVDPQPLP STNPIHSRPI FSFPKRPALR ITTEFDSEST VFFHKISCKF
     LDSLAKLKFA FHNNSKGEIA EPQISFVSKY LSLHYDLEDH SALVKSSVDV GPKLKLIGTH
     DVKAQQGEVT MVANLDDPGY ALQLSTPLPS IALPKATFKF PQGEISLQEI NDHDEDEQVK
     NSLSVSGTLK GQLLKGLCTA QYKDQEFKLR YRYKDDEMSF LPILSLPSNA LSFAFKRRFG
     PSDKLSYWYN CDSNYWSAVY KHTYGEDFKF KAGYDSEVRL GWASLWVGDE GGKAKTAPMK
     MKVQFMLQVP QDDIKSSVLM FRVKKRWDI