OEP24_PEA
ID OEP24_PEA Reviewed; 213 AA.
AC O49929;
DT 22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 43.
DE RecName: Full=Outer envelope pore protein 24, chloroplastic;
DE AltName: Full=Chloroplastic outer envelope pore protein of 24 kDa;
GN Name=OEP24;
OS Pisum sativum (Garden pea).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Fabeae; Pisum.
OX NCBI_TaxID=3888;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, BETA STRANDS, SUBCELLULAR LOCATION,
RP TISSUE SPECIFICITY, AND SUBUNIT.
RC STRAIN=cv. Golf; TISSUE=Seedling;
RX PubMed=9668138; DOI=10.2307/3870722;
RA Pohlmeyer K., Soll J., Grimm R., Hill K., Wagner R.;
RT "A high-conductance solute channel in the chloroplastic outer envelope from
RT Pea.";
RL Plant Cell 10:1207-1216(1998).
RN [2]
RP FUNCTION.
RX PubMed=10556523; DOI=10.1016/s0014-5793(99)01399-x;
RA Roehl T., Motzkus M., Soll J.;
RT "The outer envelope protein OEP24 from pea chloroplasts can functionally
RT replace the mitochondrial VDAC in yeast.";
RL FEBS Lett. 460:491-494(1999).
RN [3]
RP REVIEW ON CHLOROPLAST TRANSPORT.
RX PubMed=10748262; DOI=10.1016/s0005-2736(00)00146-2;
RA Neuhaus H.E., Wagner R.;
RT "Solute pores, ion channels, and metabolite transporters in the outer and
RT inner envelope membranes of higher plant plastids.";
RL Biochim. Biophys. Acta 1465:307-323(2000).
RN [4]
RP FUNCTION, SUBCELLULAR LOCATION, AND SUBUNIT.
RX PubMed=19602439; DOI=10.1016/j.pep.2009.07.004;
RA Liguori L., Blesneac I., Madern D., Vivaudou M., Lenormand J.-L.;
RT "Single-step production of functional OEP24 proteoliposomes.";
RL Protein Expr. Purif. 69:106-111(2010).
CC -!- FUNCTION: High-conductance voltage-dependent solute channel with a
CC slight selectivity for cations transporting triosephosphates,
CC dicarboxylic acids, ATP, inorganic phosphate (Pi), sugars, and
CC positively or negatively charged amino acids.
CC {ECO:0000269|PubMed:10556523, ECO:0000269|PubMed:19602439,
CC ECO:0000269|PubMed:9668138}.
CC -!- SUBUNIT: Homooligomers form large rather nonselective pores in
CC plastidial outer membranes. {ECO:0000269|PubMed:19602439,
CC ECO:0000269|PubMed:9668138}.
CC -!- SUBCELLULAR LOCATION: Plastid, etioplast membrane
CC {ECO:0000305|PubMed:9668138}; Multi-pass membrane protein. Plastid,
CC chloroplast outer membrane {ECO:0000269|PubMed:9668138}; Multi-pass
CC membrane protein. Note=Present in non-green root plastids.
CC -!- TISSUE SPECIFICITY: Present in roots, shoots and leaves.
CC {ECO:0000269|PubMed:9668138}.
CC -!- SIMILARITY: Belongs to the plastid outer envelope porin OEP24 (TC
CC 1.B.28) family. {ECO:0000305}.
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DR EMBL; AJ001009; CAA04468.1; -; mRNA.
DR PIR; T06474; T06474.
DR AlphaFoldDB; O49929; -.
DR TCDB; 1.B.28.1.1; the plastid outer envelope porin of 24 kda (oep24) family.
DR EnsemblPlants; Psat6g006400.1; Psat6g006400.1.cds; Psat6g006400.
DR Gramene; Psat6g006400.1; Psat6g006400.1.cds; Psat6g006400.
DR GO; GO:0034426; C:etioplast membrane; IDA:UniProtKB.
DR GO; GO:0031359; C:integral component of chloroplast outer membrane; IDA:UniProtKB.
DR GO; GO:0046930; C:pore complex; IDA:UniProtKB.
DR GO; GO:0015288; F:porin activity; IDA:UniProtKB.
DR GO; GO:0022843; F:voltage-gated cation channel activity; IDA:UniProtKB.
DR GO; GO:0034765; P:regulation of ion transmembrane transport; IDA:UniProtKB.
DR InterPro; IPR034626; OEP24.
DR PANTHER; PTHR35284; PTHR35284; 1.
PE 1: Evidence at protein level;
KW Chloroplast; Ion transport; Membrane; Plastid; Plastid outer membrane;
KW Porin; Transmembrane; Transmembrane beta strand; Transport.
FT CHAIN 1..213
FT /note="Outer envelope pore protein 24, chloroplastic"
FT /id="PRO_0000415538"
FT TOPO_DOM 1
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 2..11
FT /note="Beta stranded; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 12..17
FT /note="Chloroplast intermembrane"
FT /evidence="ECO:0000255"
FT TRANSMEM 18..27
FT /note="Beta stranded; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 28..31
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 32..41
FT /note="Beta stranded; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 42..54
FT /note="Chloroplast intermembrane"
FT /evidence="ECO:0000255"
FT TRANSMEM 55..63
FT /note="Beta stranded; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 64..69
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..79
FT /note="Beta stranded; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 80..92
FT /note="Chloroplast intermembrane"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..102
FT /note="Beta stranded; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 103..107
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 108..117
FT /note="Beta stranded; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 118..121
FT /note="Chloroplast intermembrane"
FT /evidence="ECO:0000255"
FT TRANSMEM 122..131
FT /note="Beta stranded; Name=8"
FT /evidence="ECO:0000255"
FT TOPO_DOM 132..143
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 144..155
FT /note="Beta stranded; Name=9"
FT /evidence="ECO:0000255"
FT TOPO_DOM 156..158
FT /note="Chloroplast intermembrane"
FT /evidence="ECO:0000255"
FT TRANSMEM 159..167
FT /note="Beta stranded; Name=10"
FT /evidence="ECO:0000255"
FT TOPO_DOM 168..169
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 170..178
FT /note="Beta stranded; Name=11"
FT /evidence="ECO:0000255"
FT TOPO_DOM 179..201
FT /note="Chloroplast intermembrane"
FT /evidence="ECO:0000255"
FT TRANSMEM 202..211
FT /note="Beta stranded; Name=12"
FT /evidence="ECO:0000255"
FT TOPO_DOM 212..213
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 213 AA; 23382 MW; 6FD15A755F1A21E8 CRC64;
MKAALKGKYD LDHNSSGAAT VAFNAGDVKL RASITDATFK NSPSLTGLVL AVEKPGSFSV
DYNVPKKDFR FQFMNTVRVA EKPLNLAYIH SKGDNRTILD GTLVWDPSNK VSANYAVESG
NCKLKYSYNH KGLTTIEPTY DVAKNSWDFA VSGKVYGDDS LKASYQTSSK VLGLEWTRNS
KQTGCFKVVA SVNLAEEKKI PKLSVESTLN FEM
