ID   NUDC_DICDI              Reviewed;         171 AA.
AC   Q54M64;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Nuclear movement protein nudC;
DE   AltName: Full=Nuclear distribution protein C homolog;
GN   Name=nudc; ORFNames=DDB_G0286159;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Required for nuclear movement. May interact between
CC       microtubules and nuclei and/or may be involved in the generation of
CC       force used to move nuclei during interphase (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the nudC family. {ECO:0000305}.
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DR   EMBL; AAFI02000085; EAL64372.1; -; Genomic_DNA.
DR   RefSeq; XP_637884.1; XM_632792.1.
DR   AlphaFoldDB; Q54M64; -.
DR   SMR; Q54M64; -.
DR   STRING; 44689.DDB0266415; -.
DR   PaxDb; Q54M64; -.
DR   EnsemblProtists; EAL64372; EAL64372; DDB_G0286159.
DR   GeneID; 8625481; -.
DR   KEGG; ddi:DDB_G0286159; -.
DR   dictyBase; DDB_G0286159; nudc.
DR   eggNOG; KOG2265; Eukaryota.
DR   HOGENOM; CLU_047332_2_0_1; -.
DR   InParanoid; Q54M64; -.
DR   OMA; WTLETTP; -.
DR   PhylomeDB; Q54M64; -.
DR   Reactome; R-DDI-9648025; EML4 and NUDC in mitotic spindle formation.
DR   PRO; PR:Q54M64; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0000741; P:karyogamy; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR007052; CS_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   InterPro; IPR037898; NudC_fam.
DR   PANTHER; PTHR12356; PTHR12356; 1.
DR   Pfam; PF04969; CS; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
DR   PROSITE; PS51203; CS; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Cytoskeleton; Karyogamy; Microtubule;
KW   Mitosis; Reference proteome.
FT   CHAIN           1..171
FT                   /note="Nuclear movement protein nudC"
FT                   /id="PRO_0000327735"
FT   DOMAIN          8..98
FT                   /note="CS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00547"
SQ   SEQUENCE   171 AA;  19921 MW;  8CC6D247EDE5E5F3 CRC64;
     MSKESQVNKC DRYTWSQTLN DCTLSIKLEN PVKSKDLFIK IDNDHLTVKN LITNDTIIDG
     KLYKNVKKSD CNWTLESGKN LEIELFKLKG QEWWSCIIQG ESEIDVTQIK PQNSSLSDFD
     GETRAMVEKM LYNQNRKAQG LPTTDEEEKQ RIFETFKNEH PDMDFSNAKF N