ID   NPRL3_SCHPO             Reviewed;         585 AA.
AC   Q9HGM7;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=Nitrogen permease regulator 3-like protein;
GN   ORFNames=SPBC543.04;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- SIMILARITY: Belongs to the NPR3 family. {ECO:0000305}.
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DR   EMBL; CU329671; CAC05246.1; -; Genomic_DNA.
DR   RefSeq; NP_596792.1; NM_001023812.2.
DR   AlphaFoldDB; Q9HGM7; -.
DR   SMR; Q9HGM7; -.
DR   BioGRID; 277588; 5.
DR   STRING; 4896.SPBC543.04.1; -.
DR   MaxQB; Q9HGM7; -.
DR   PaxDb; Q9HGM7; -.
DR   EnsemblFungi; SPBC543.04.1; SPBC543.04.1:pep; SPBC543.04.
DR   PomBase; SPBC543.04; -.
DR   VEuPathDB; FungiDB:SPBC543.04; -.
DR   eggNOG; KOG3830; Eukaryota.
DR   HOGENOM; CLU_014314_1_0_1; -.
DR   InParanoid; Q9HGM7; -.
DR   OMA; CLPQKVH; -.
DR   PhylomeDB; Q9HGM7; -.
DR   PRO; PR:Q9HGM7; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0097042; C:extrinsic component of fungal-type vacuolar membrane; IBA:GO_Central.
DR   GO; GO:1990130; C:GATOR1 complex; IMP:PomBase.
DR   GO; GO:0005774; C:vacuolar membrane; EXP:PomBase.
DR   GO; GO:0034198; P:cellular response to amino acid starvation; IBA:GO_Central.
DR   GO; GO:1904262; P:negative regulation of TORC1 signaling; IMP:PomBase.
DR   GO; GO:0010508; P:positive regulation of autophagy; IBA:GO_Central.
DR   GO; GO:0050790; P:regulation of catalytic activity; IEA:GOC.
DR   GO; GO:0038202; P:TORC1 signaling; IBA:GO_Central.
DR   InterPro; IPR005365; Npr3.
DR   PANTHER; PTHR13153; PTHR13153; 2.
DR   Pfam; PF03666; NPR3; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..585
FT                   /note="Nitrogen permease regulator 3-like protein"
FT                   /id="PRO_0000220641"
FT   REGION          117..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        129..157
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   585 AA;  66869 MW;  92F53DFB5AC1BE59 CRC64;
     MVRLTPRLVA IFLVEKTTSG ANFVFHWPLQ PQVRLQATHH NNDSAESAIG MLDLDDSDDD
     ENNRFTEVAD DTHVLGYEKG FLANMLSPRI ELCNQKFEIW VDGLTFLGCP VHIGPNGEWA
     KRRKPRTTVE SNASSSHLVS KPESSHPSTG SFEVKSSSSK SRSSMSLFHV VFVLNVPTAT
     VYRPTVNTMY DHIVVKLVTG LKYEQAKRNY VENECIHILK LTEKYSSQNV PFDVYAAQIP
     HHSNLASVLA TTYEALINMH TAYLEINQSI NLSLLWPMSV STNTLENYEL QVRPSTILAS
     QTIFSEEHPS SIEPFVAPYW TLLLLKDTDT IMKRVPLLQN SLLSSFIAIV KPNLTFTDIA
     NRLGISVSEC FILAKHLIHW RKAIAIPPLL IRNTYVTSPT ANLFNLEEES KLFKKEFPSL
     PSLSTFLAIL SFKPRPFASI IPSKDHELVY LEMLAWLCRR NWVYEQNIYM YILVPEEIKK
     KAIALIESDE SSKNDMQLRK QLEQDNGKES IIIDPHSASL LEQKWIQIIA YERGPEMAPL
     FTSIVKYLNG RFALQTIWVA EGLPRKLMRN ILNEYNDYIL RWHSW