NPR4_ORYSJ
ID NPR4_ORYSJ Reviewed; 583 AA.
AC A2CIR5; Q0JHX9; Q5QMH5;
DT 07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT 20-FEB-2007, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Ankyrin repeat-containing protein NPR4 {ECO:0000305};
DE Short=OsNPR4 {ECO:0000303|PubMed:17309686};
GN Name=NPR4 {ECO:0000303|PubMed:17309686};
GN OrderedLocusNames=Os01g0837000 {ECO:0000312|EMBL:BAS75114.1},
GN LOC_Os01g61990 {ECO:0000305};
GN ORFNames=P0506B12.37 {ECO:0000312|EMBL:BAD73402.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1).
RX PubMed=17309686; DOI=10.1111/j.1467-7652.2007.00243.x;
RA Yuan Y., Zhong S., Li Q., Zhu Z., Lou Y., Wang L., Wang J., Wang M., Li Q.,
RA Yang D., He Z.;
RT "Functional analysis of rice NPR1-like genes reveals that OsNPR1/NH1 is the
RT rice orthologue conferring disease resistance with enhanced herbivore
RT susceptibility.";
RL Plant Biotechnol. J. 5:313-324(2007).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Nipponbare;
RG The rice full-length cDNA consortium;
RT "Oryza sativa full length cDNA.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in salt stress tolerance.
CC {ECO:0000250|UniProtKB:Q9C7A2}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q9C7A2};
CC Multi-pass membrane protein {ECO:0000255}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=A2CIR5-1; Sequence=Displayed;
CC Name=2;
CC IsoId=A2CIR5-2; Sequence=VSP_058478;
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF06649.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; DQ450953; ABE11619.1; -; mRNA.
DR EMBL; DQ450954; ABE11620.1; -; Genomic_DNA.
DR EMBL; AP003271; BAD73402.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF06649.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014957; BAS75114.1; -; Genomic_DNA.
DR EMBL; AK243678; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015622043.1; XM_015766557.1. [A2CIR5-2]
DR AlphaFoldDB; A2CIR5; -.
DR SMR; A2CIR5; -.
DR STRING; 4530.OS01T0837000-01; -.
DR PRIDE; A2CIR5; -.
DR EnsemblPlants; Os01t0837000-01; Os01t0837000-01; Os01g0837000. [A2CIR5-2]
DR GeneID; 4327365; -.
DR Gramene; Os01t0837000-01; Os01t0837000-01; Os01g0837000. [A2CIR5-2]
DR KEGG; osa:4327365; -.
DR eggNOG; KOG0504; Eukaryota.
DR OMA; CEESCEI; -.
DR OrthoDB; 570510at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.20; -; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR026961; PGG_dom.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF13962; PGG; 1.
DR SMART; SM00248; ANK; 7.
DR SUPFAM; SSF48403; SSF48403; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 3.
PE 2: Evidence at transcript level;
KW Alternative splicing; ANK repeat; Cell membrane; Membrane;
KW Reference proteome; Repeat; Stress response; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..583
FT /note="Ankyrin repeat-containing protein NPR4"
FT /id="PRO_0000437006"
FT TRANSMEM 414..434
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 452..472
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 492..512
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 518..538
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REPEAT 68..97
FT /note="ANK 1"
FT /evidence="ECO:0000255"
FT REPEAT 119..148
FT /note="ANK 2"
FT /evidence="ECO:0000255"
FT REPEAT 154..183
FT /note="ANK 3"
FT /evidence="ECO:0000255"
FT REPEAT 188..218
FT /note="ANK 4"
FT /evidence="ECO:0000255"
FT REPEAT 223..252
FT /note="ANK 5"
FT /evidence="ECO:0000255"
FT REPEAT 257..286
FT /note="ANK 6"
FT /evidence="ECO:0000255"
FT REPEAT 291..321
FT /note="ANK 7"
FT /evidence="ECO:0000255"
FT VAR_SEQ 1..34
FT /note="MVSDRSCIGYLRSVIAGSVDTHTGHECTITNHAA -> MSLEIHE (in
FT isoform 2)"
FT /id="VSP_058478"
SQ SEQUENCE 583 AA; 63291 MW; 6F24B0F92F06F0F0 CRC64;
MVSDRSCIGY LRSVIAGSVD THTGHECTIT NHAAEEGGGT AAAAAVKVMT VSGSGKRGRY
VRQVTGRHND TDLHVAARGG DAGALRRALD EAAAAVATGE GREALEEVRR AVAAEPNEAG
ETPLVAAAER GHLEVVRELL RHLDAEGVAA KNRSGYDALH VAAREGRHAV VQEMLLHNRL
LAKTFGPANT SPLISAATRG HTEVVKLLLE LDDFGLVEMA KDNGKNSLHF AARQGHVEIV
KALLEKDPQL ARRNDKKGQT ALHMAVKGTN CDVLRALVDA DPAIVMLPDK NGNTALHVAT
RKKRAEIVAV LLRLPDTHVN ALTRDHKTAY DIAEALPLCE ESSEIKDILS QHGALRSREL
NQPRDELRKT VTEIKKDVHT QLEQTRKTNK NVHGIAKELR KLHREGINNA TNSVTVVAVL
FATVAFAAIF TVPGGNANNG VAVVVQAASF RIFFIFNAIA LFTSLAVVVV QITVVRGETK
SERKVVEVIN KLMWLASVCT TISFIASCYI VLGRHFQWAA LLVSLIGGIT MAGVLGTMTY
YVVKSKRMRK IRKKEKMSRR SGSSSWYDNT ELSETELNQV YAL
