ID   NPR3_PHANO              Reviewed;         870 AA.
AC   Q0TZN8;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Nitrogen permease regulator 3;
DE   AltName: Full=Required for meiotic nuclear division protein 11;
DE   Flags: Precursor;
GN   Name=NPR3; Synonyms=RMD11; ORFNames=SNOG_15055;
OS   Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS   blotch fungus) (Parastagonospora nodorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC   Parastagonospora.
OX   NCBI_TaxID=321614;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX   PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA   Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA   Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA   Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT   "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT   analysis of the wheat pathogen Stagonospora nodorum.";
RL   Plant Cell 19:3347-3368(2007).
CC   -!- FUNCTION: Mediates inactivation of the TORC1 complex in response to
CC       amino acid starvation. Required for meiotic nuclear division (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NPR3 family. {ECO:0000305}.
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DR   EMBL; CH445359; EAT77598.1; -; Genomic_DNA.
DR   RefSeq; XP_001805218.1; XM_001805166.1.
DR   AlphaFoldDB; Q0TZN8; -.
DR   STRING; 13684.SNOT_15055; -.
DR   EnsemblFungi; SNOT_15055; SNOT_15055; SNOG_15055.
DR   GeneID; 5982146; -.
DR   KEGG; pno:SNOG_15055; -.
DR   eggNOG; KOG3830; Eukaryota.
DR   HOGENOM; CLU_014314_1_0_1; -.
DR   InParanoid; Q0TZN8; -.
DR   OMA; ARTDYVW; -.
DR   OrthoDB; 628619at2759; -.
DR   Proteomes; UP000001055; Unassembled WGS sequence.
DR   GO; GO:0097042; C:extrinsic component of fungal-type vacuolar membrane; IBA:GO_Central.
DR   GO; GO:1990130; C:GATOR1 complex; IBA:GO_Central.
DR   GO; GO:0034198; P:cellular response to amino acid starvation; IBA:GO_Central.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:1904262; P:negative regulation of TORC1 signaling; IBA:GO_Central.
DR   GO; GO:0010508; P:positive regulation of autophagy; IBA:GO_Central.
DR   GO; GO:0038202; P:TORC1 signaling; IBA:GO_Central.
DR   InterPro; IPR005365; Npr3.
DR   PANTHER; PTHR13153; PTHR13153; 1.
DR   Pfam; PF03666; NPR3; 1.
PE   3: Inferred from homology;
KW   Meiosis; Reference proteome; Signal.
FT   SIGNAL          1..?
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..870
FT                   /note="Nitrogen permease regulator 3"
FT                   /id="PRO_0000301804"
FT   REGION          56..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          253..283
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          642..768
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        99..118
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        259..283
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        674..718
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        738..753
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   870 AA;  96601 MW;  084F66AC41224ED9 CRC64;
     MALPLPPASN LHSILLVTKS RSLGPRLVFH YPPLSPSAAA LAGAKDPAWY RHDVSTASIG
     SGSSDSEWDS STATDDDNDV EIGSRTSGGR GSGRTLTGAS FRDRDRSKLG TEVWNKQETI
     DEDDPDDEDG DRNGRNRRRG GDYDWDTVLG FKTDALEKML SPGKEFNKRR FELGVESIVF
     VGAPMFVRED GLWKKLKRRK KKRSDKEKLD DADFVKNLTI SEEDEEADTV DEIPVKSKPE
     PFVYPEGFEP GYGHGSISSG PSGAPSEAGS DARSNSTSQD NNPDMNMFNV VFVLNPPALE
     YQQRVKEMYD NVTRKYAKAL KYEEARFQYV WKESKRIIDL KQRAKESNES LTSTWRKIIS
     TSPLAKSIAI MFDAISHDKI AHIHFDATFN TSFQIPQADS TPYLPTALEP QMPGLWLTTS
     NVVLADDESP MTQHAALLLL EDTETLIKDL GGEVTGNAAA IAFYIRNIIP TKSLLKISKR
     HNISAHDMEY IASHLVYWRR ARLIAPLSPR DTYIVSPNAD FSLLPSAVTA YAQRFPTLPT
     LPKVLNMLSG TPRPFRNFIP TTEHREAYMD ILAWLMRGGW VTQLRTFAWV RVTPEIKAKV
     AAEMEREERI KKAEEARKEL LSDNESVAES LLSDKRSSLL SAGTVRSSTP LRMAHRDRGT
     GGLGEEDMHH STILSPRITA SAAPSYRGSP TRASSDAGST SSQRTTIALS SSQRPDSPSR
     LGVRDVKPHR PSPLHLHPTS PSRGSAVSLA SPTATSPPPS PKDFKPSIVY SPQKATSLEA
     RWLEKIGQSF EDVGNIIPTP NPSPPKGQDG GMFGITGKEL REAWPILLKH LDGRHAIEDV
     APRENMKRKR VAAMYNTIKE RGWLVVVRHW