ID   NIFE_SINFN              Reviewed;         496 AA.
AC   P55673;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE;
GN   Name=nifE; OrderedLocusNames=NGR_a01100; ORFNames=y4vN;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OG   Plasmid sym pNGR234a.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=9163424; DOI=10.1038/387394a0;
RA   Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A.,
RA   Perret X.;
RT   "Molecular basis of symbiosis between Rhizobium and legumes.";
RL   Nature 387:394-401(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/aem.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion
RT   systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- FUNCTION: This protein may play a role in the biosynthesis of the
CC       prosthetic group of nitrogenase (FeMo cofactor).
CC   -!- PATHWAY: Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.
CC   -!- SIMILARITY: Belongs to the NifD/NifK/NifE/NifN family. {ECO:0000305}.
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DR   EMBL; U00090; AAB91902.1; -; Genomic_DNA.
DR   RefSeq; NP_444115.1; NC_000914.2.
DR   RefSeq; WP_010875151.1; NC_000914.2.
DR   AlphaFoldDB; P55673; -.
DR   SMR; P55673; -.
DR   STRING; 394.NGR_a01100; -.
DR   EnsemblBacteria; AAB91902; AAB91902; NGR_a01100.
DR   KEGG; rhi:NGR_a01100; -.
DR   PATRIC; fig|394.7.peg.94; -.
DR   eggNOG; COG2710; Bacteria.
DR   HOGENOM; CLU_025876_1_1_5; -.
DR   OMA; SWDNRGT; -.
DR   OrthoDB; 363662at2; -.
DR   UniPathway; UPA00782; -.
DR   Proteomes; UP000001054; Plasmid sym pNGR234a.
DR   GO; GO:0016163; F:nitrogenase activity; IEA:InterPro.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR   InterPro; IPR000510; Nase/OxRdtase_comp1.
DR   InterPro; IPR000318; Nase_comp1_CS.
DR   InterPro; IPR005973; NifE.
DR   Pfam; PF00148; Oxidored_nitro; 1.
DR   TIGRFAMs; TIGR01283; nifE; 1.
DR   PROSITE; PS00699; NITROGENASE_1_1; 1.
DR   PROSITE; PS00090; NITROGENASE_1_2; 1.
PE   3: Inferred from homology;
KW   Nitrogen fixation; Plasmid; Reference proteome.
FT   CHAIN           1..496
FT                   /note="Nitrogenase iron-molybdenum cofactor biosynthesis
FT                   protein NifE"
FT                   /id="PRO_0000153122"
FT   REGION          455..491
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        465..479
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   496 AA;  54794 MW;  D78472D8F5410A3A CRC64;
     MSSLNVKIQD VFDEPACERN RSKDSNARSK GCSKPLTPGA AAGGCAFDGA KIVLQPITDV
     AHLVHAPLAC EGNSWDNRGT ASSGPTLWRT SFTTDLTEQD IVMGNSERKL FKAIRQIREA
     YQPPAIFVYA TCVTALIGDD IEAICKRAEE TCGLPVVPIN SPGFVGSKNL GNKLAGEALL
     DHVIGTVEPD DAGPCDINIL GEFNLSGEFW LVKPLLERLG IRVRACIPGD ARYLDIASAH
     RARAAMLVCS TALINLARKM EERWDIPFFE GSFYGITATS EALRQIADLL VKKGTDLEIL
     DRTDALIAEE EAIAWKKLEE YRPRLKGKRV LINTGGVKSW SLVHALMEIG MEIVGTSVKK
     STVEDKERIR QVLKDDLQMF ESMSPRELYA MLSEHKADIM LSGGRTQFIA LKAKMPWVDI
     NQERHRPYAG YDGTVELVRQ IDLAIHNPVW SQVREPAPWE SRPATQEPLP NTRPDTDATS
     VGRSIRRHDA GDFVEC