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NFUA_KLEPN
ID   NFUA_KLEPN              Reviewed;         100 AA.
AC   Q9EXI9;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Fe/S biogenesis protein NfuA;
DE   Flags: Fragment;
GN   Name=nfuA; Synonyms=yhgI;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CG43;
RX   PubMed=11598090; DOI=10.1128/iai.69.11.7140-7145.2001;
RA   Lai Y.-C., Peng H.-L., Chang H.-Y.;
RT   "Identification of genes induced in vivo during Klebsiella pneumoniae CG43
RT   infection.";
RL   Infect. Immun. 69:7140-7145(2001).
CC   -!- FUNCTION: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S
CC       cluster, can transfer this cluster to apoproteins, and thereby
CC       intervenes in the maturation of Fe/S proteins. Could also act as a
CC       scaffold/chaperone for damaged Fe/S proteins (By similarity).
CC       {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000250};
CC       Note=Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably
CC       bound at the interface of two monomers. {ECO:0000250};
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NfuA family. {ECO:0000305}.
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DR   EMBL; AJ292303; CAC19417.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9EXI9; -.
DR   SMR; Q9EXI9; -.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.300.12; -; 1.
DR   InterPro; IPR000361; FeS_biogenesis.
DR   InterPro; IPR035903; HesB-like_dom_sf.
DR   Pfam; PF01521; Fe-S_biosyn; 1.
DR   SUPFAM; SSF89360; SSF89360; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding.
FT   CHAIN           1..>100
FT                   /note="Fe/S biogenesis protein NfuA"
FT                   /id="PRO_0000209477"
FT   NON_TER         100
SQ   SEQUENCE   100 AA;  10919 MW;  CA618E9EB4EC3527 CRC64;
     MIRISDAAQA HFAKLLANQE EGTQIRVFVI NPGTPNAECG VSYCPPDAVE DTDTALKFEQ
     LTAYVDELSA PYLEDAEIDF VTDQLGSQLT LKARTPKCAK
 
 
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