ID   NDE1_YARLI              Reviewed;         461 AA.
AC   Q6C3S1;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Nuclear distribution protein nudE homolog 1;
GN   Name=NDE1; OrderedLocusNames=YALI0E32571g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for nuclear migration. {ECO:0000250}.
CC   -!- SUBUNIT: Self-associates. Interacts with PAC1 (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. Note=Localizes to the
CC       plus ends of microtubules. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the nudE family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR382131; CAG80295.1; -; Genomic_DNA.
DR   RefSeq; XP_504691.1; XM_504691.1.
DR   AlphaFoldDB; Q6C3S1; -.
DR   SMR; Q6C3S1; -.
DR   STRING; 4952.CAG80295; -.
DR   EnsemblFungi; CAG80295; CAG80295; YALI0_E32571g.
DR   GeneID; 2911652; -.
DR   KEGG; yli:YALI0E32571g; -.
DR   VEuPathDB; FungiDB:YALI0_E32571g; -.
DR   HOGENOM; CLU_593407_0_0_1; -.
DR   InParanoid; Q6C3S1; -.
DR   OMA; NANDDIE; -.
DR   Proteomes; UP000001300; Chromosome E.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005871; C:kinesin complex; IBA:GO_Central.
DR   GO; GO:0000776; C:kinetochore; IBA:GO_Central.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR   GO; GO:0016477; P:cell migration; IBA:GO_Central.
DR   GO; GO:0051642; P:centrosome localization; IBA:GO_Central.
DR   GO; GO:0007059; P:chromosome segregation; IBA:GO_Central.
DR   GO; GO:0051303; P:establishment of chromosome localization; IBA:GO_Central.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IBA:GO_Central.
DR   GO; GO:0007020; P:microtubule nucleation; IBA:GO_Central.
DR   GO; GO:0047496; P:vesicle transport along microtubule; IBA:GO_Central.
DR   InterPro; IPR033494; NUDE.
DR   PANTHER; PTHR10921; PTHR10921; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Microtubule; Reference proteome;
KW   Transport.
FT   CHAIN           1..461
FT                   /note="Nuclear distribution protein nudE homolog 1"
FT                   /id="PRO_0000240228"
FT   REGION          266..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          316..461
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          21..206
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        281..300
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        319..336
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        394..426
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   461 AA;  50801 MW;  667EAF019D7D2DB7 CRC64;
     MTDIDTPASP LTPNSKAHLE VIAYNQYLQA KEQIQQLEHE LTEFQESSKE LELELEQELA
     ESDKRQAKLE DRISALESEV TEWRKKALDA HKEAASTQQA LQREVSSLRD AHKLVKERLR
     ETENANDDIE QRERITCSTL EDIQTRYNEA LENVAILEAE LAAKDVLIGE HHRAKEEIKD
     LTEELEHTRK KLAIRDQELE DANKRIMNPP PATNHNATTH RRAVSGTAQV SAEGYLTPLT
     STGAKPLSSS RSMQFIHGLQ SQMRSLESRV AHVKSSLPKP TTPKRAKSSA SAVSGASTIK
     SSPSMALLTR KLSEADDVVS LSPSRSTSSL EDLCTPSPSP QVARRDMSGG GSRLDLRADP
     RLNGRPKTQQ PRPSYNSALA TAKPLDPIEG SPTSLEGRNR TRSASPTKKL SSLSLNAPSL
     PQSQARVNIP ALMRPASPIK QPSPPKPAPG SKFADVYGRR R