ID   NDE1B_XENLA             Reviewed;         349 AA.
AC   Q6NRJ5;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-JUN-2006, sequence version 2.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Nuclear distribution protein nudE homolog 1-B;
GN   Name=nde1-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Oocyte;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for centrosome duplication and formation and
CC       function of the mitotic spindle. {ECO:0000250}.
CC   -!- SUBUNIT: Self-associates. Interacts with pafah1b1 (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm,
CC       cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.
CC       Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=Localizes to the
CC       interphase centrosome and to the mitotic spindle. {ECO:0000250}.
CC   -!- PTM: Phosphorylated in mitosis. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the nudE family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH70755.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC070755; AAH70755.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001084910.2; NM_001091441.1.
DR   RefSeq; XP_018092901.1; XM_018237412.1.
DR   RefSeq; XP_018092902.1; XM_018237413.1.
DR   AlphaFoldDB; Q6NRJ5; -.
DR   SMR; Q6NRJ5; -.
DR   DNASU; 431961; -.
DR   GeneID; 431961; -.
DR   KEGG; xla:431961; -.
DR   CTD; 431961; -.
DR   Xenbase; XB-GENE-1005621; nde1.S.
DR   OMA; CERPATL; -.
DR   OrthoDB; 1082224at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10S.
DR   Bgee; 431961; Expressed in blastula and 19 other tissues.
DR   GO; GO:0005813; C:centrosome; TAS:AgBase.
DR   GO; GO:0005737; C:cytoplasm; TAS:AgBase.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0031616; C:spindle pole centrosome; ISS:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0051298; P:centrosome duplication; ISS:UniProtKB.
DR   GO; GO:0010842; P:retina layer formation; TAS:AgBase.
DR   InterPro; IPR033494; NUDE.
DR   InterPro; IPR006964; NUDE_dom.
DR   PANTHER; PTHR10921; PTHR10921; 1.
DR   Pfam; PF04880; NUDE_C; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Coiled coil; Cytoplasm; Cytoskeleton;
KW   Microtubule; Mitosis; Phosphoprotein; Reference proteome.
FT   CHAIN           1..349
FT                   /note="Nuclear distribution protein nudE homolog 1-B"
FT                   /id="PRO_0000240207"
FT   COILED          22..189
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   349 AA;  39724 MW;  72759B7816634000 CRC64;
     MDDLENIIFN SVEEEIIYWK SVAMKYKQCS EEAQQELQEF QEASREYEAE LEAQLQQTEG
     RNRDIFSENN RLRMELDSIK EKYEEQHSEN YIQISTLEGD LSTTKAVRDQ LQKYIRELEQ
     ANDDLERAKR ATIMSLEDFE QRLNQAIERN AFLESELDEK ENVLESVQRL KDEARDLRQE
     LAVQQKQEKP KSNMVSPETE RMDTSVQASI AIPLAPLTPL SQRGCASTLN SPLSFKTSWD
     DGYSGTPLTP CARISALNIV GDLLRKVGAL ESKLASCRNF VHEQSPNRPL TSVSARMNKT
     REGIENRLSI ASGSSVEKGL IKRLEFGSLP SNTPMQGMRS PQGVVKIII