NCKP5_HUMAN
ID NCKP5_HUMAN Reviewed; 1909 AA.
AC O14513; B8ZZL0; Q29SS9; Q29ST0; Q2NL90; Q6ZVE2; Q8NAS3;
DT 16-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT 28-NOV-2006, sequence version 2.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Nck-associated protein 5;
DE Short=NAP-5;
DE AltName: Full=Peripheral clock protein;
GN Name=NCKAP5; Synonyms=ERIH, NAP5;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), AND NUCLEOTIDE SEQUENCE
RP [LARGE SCALE MRNA] OF 1586-1909 (ISOFORM 1).
RC TISSUE=Amygdala, and Teratocarcinoma;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT 4.";
RL Nature 434:724-731(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 6-1909 (ISOFORM 4).
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 69-1909 (ISOFORMS 1 AND 2).
RA Hisa T.;
RL Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 661-1077 (ISOFORM 1).
RC TISSUE=Brain;
RX PubMed=9344857; DOI=10.1006/bbrc.1997.7492;
RA Matuoka K., Miki H., Takahashi K., Takenawa T.;
RT "A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2
RT domain and nuclear signaling motifs.";
RL Biochem. Biophys. Res. Commun. 239:488-492(1997).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Leukemic T-cell;
RX PubMed=19690332; DOI=10.1126/scisignal.2000007;
RA Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,
RA Rodionov V., Han D.K.;
RT "Quantitative phosphoproteomic analysis of T cell receptor signaling
RT reveals system-wide modulation of protein-protein interactions.";
RL Sci. Signal. 2:RA46-RA46(2009).
RN [7]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Cervix carcinoma;
RX PubMed=23186163; DOI=10.1021/pr300630k;
RA Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA Mohammed S.;
RT "Toward a comprehensive characterization of a human cancer cell
RT phosphoproteome.";
RL J. Proteome Res. 12:260-271(2013).
CC -!- SUBUNIT: Interacts with the SH3-containing region of the adapter
CC protein NCK.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=4;
CC Name=1; Synonyms=Peripheral clock protein 2, ERIH2;
CC IsoId=O14513-1; Sequence=Displayed;
CC Name=2; Synonyms=Peripheral clock protein 1, ERIH1;
CC IsoId=O14513-2; Sequence=VSP_021606;
CC Name=3;
CC IsoId=O14513-3; Sequence=VSP_021601, VSP_021604, VSP_021605;
CC Name=4;
CC IsoId=O14513-4; Sequence=VSP_021602, VSP_021603;
CC -!- TISSUE SPECIFICITY: Expressed in fetal and adult brain, leukocytes and
CC fetal fibroblasts.
CC -!- CAUTION: It is uncertain whether Met-1 or Met-26 is the initiator.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA22433.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=BAC85920.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AK057980; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AK092189; BAC03824.1; -; mRNA.
DR EMBL; AK124659; BAC85920.1; ALT_INIT; mRNA.
DR EMBL; AC010890; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC010974; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC011243; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC011755; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC011996; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC012489; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC016909; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC110831; AAI10832.1; -; mRNA.
DR EMBL; AY946007; AAY23346.1; -; mRNA.
DR EMBL; AY946008; AAY23347.1; -; mRNA.
DR EMBL; AB005217; BAA22433.1; ALT_FRAME; mRNA.
DR CCDS; CCDS46417.1; -. [O14513-2]
DR CCDS; CCDS46418.1; -. [O14513-1]
DR RefSeq; NP_997246.2; NM_207363.2. [O14513-1]
DR RefSeq; NP_997364.3; NM_207481.3. [O14513-2]
DR RefSeq; XP_016859469.1; XM_017003980.1.
DR AlphaFoldDB; O14513; -.
DR SMR; O14513; -.
DR BioGRID; 131288; 30.
DR IntAct; O14513; 10.
DR MINT; O14513; -.
DR STRING; 9606.ENSP00000387128; -.
DR GlyConnect; 758; 1 N-Linked glycan (1 site).
DR GlyGen; O14513; 2 sites, 2 N-linked glycans (1 site), 2 O-linked glycans (1 site).
DR iPTMnet; O14513; -.
DR PhosphoSitePlus; O14513; -.
DR BioMuta; NCKAP5; -.
DR jPOST; O14513; -.
DR MassIVE; O14513; -.
DR MaxQB; O14513; -.
DR PaxDb; O14513; -.
DR PeptideAtlas; O14513; -.
DR PRIDE; O14513; -.
DR ProteomicsDB; 48057; -. [O14513-1]
DR ProteomicsDB; 48058; -. [O14513-2]
DR ProteomicsDB; 48059; -. [O14513-3]
DR ProteomicsDB; 48060; -. [O14513-4]
DR Antibodypedia; 50647; 42 antibodies from 11 providers.
DR DNASU; 344148; -.
DR Ensembl; ENST00000409213.5; ENSP00000386952.1; ENSG00000176771.18. [O14513-2]
DR Ensembl; ENST00000409261.6; ENSP00000387128.1; ENSG00000176771.18. [O14513-1]
DR GeneID; 344148; -.
DR KEGG; hsa:344148; -.
DR MANE-Select; ENST00000409261.6; ENSP00000387128.1; NM_207363.3; NP_997246.2.
DR UCSC; uc002ttp.3; human. [O14513-1]
DR CTD; 344148; -.
DR DisGeNET; 344148; -.
DR GeneCards; NCKAP5; -.
DR HGNC; HGNC:29847; NCKAP5.
DR HPA; ENSG00000176771; Group enriched (brain, lung).
DR MIM; 608789; gene.
DR neXtProt; NX_O14513; -.
DR OpenTargets; ENSG00000176771; -.
DR PharmGKB; PA165696957; -.
DR VEuPathDB; HostDB:ENSG00000176771; -.
DR eggNOG; ENOG502QWN7; Eukaryota.
DR GeneTree; ENSGT00530000063607; -.
DR HOGENOM; CLU_002885_0_0_1; -.
DR InParanoid; O14513; -.
DR OMA; RRDWAQC; -.
DR OrthoDB; 29694at2759; -.
DR PhylomeDB; O14513; -.
DR TreeFam; TF331208; -.
DR PathwayCommons; O14513; -.
DR SignaLink; O14513; -.
DR BioGRID-ORCS; 344148; 10 hits in 1068 CRISPR screens.
DR ChiTaRS; NCKAP5; human.
DR GenomeRNAi; 344148; -.
DR Pharos; O14513; Tbio.
DR PRO; PR:O14513; -.
DR Proteomes; UP000005640; Chromosome 2.
DR RNAct; O14513; protein.
DR Bgee; ENSG00000176771; Expressed in corpus callosum and 99 other tissues.
DR ExpressionAtlas; O14513; baseline and differential.
DR Genevisible; O14513; HS.
DR GO; GO:0035371; C:microtubule plus-end; IBA:GO_Central.
DR GO; GO:0001578; P:microtubule bundle formation; IBA:GO_Central.
DR GO; GO:0007019; P:microtubule depolymerization; IBA:GO_Central.
DR InterPro; IPR032769; NCKAP5_C.
DR InterPro; IPR026163; Nckap5l.
DR PANTHER; PTHR21740; PTHR21740; 1.
DR Pfam; PF15246; NCKAP5; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Coiled coil; Reference proteome.
FT CHAIN 1..1909
FT /note="Nck-associated protein 5"
FT /id="PRO_0000096711"
FT REGION 351..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 736..819
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 855..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1026..1469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1486..1509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1541..1592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1725..1750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1763..1885
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 71..253
FT /evidence="ECO:0000255"
FT COMPBIAS 749..808
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 885..904
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 947..965
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1046..1134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1178..1192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1273..1328
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1347..1366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1424..1466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1541..1574
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1577..1592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1763..1792
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1811..1830
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1863..1882
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..25
FT /note="Missing (in isoform 3)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_021601"
FT VAR_SEQ 115..118
FT /note="MEET -> RRKM (in isoform 4)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_021602"
FT VAR_SEQ 119..1909
FT /note="Missing (in isoform 4)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_021603"
FT VAR_SEQ 194..203
FT /note="AENSALALEN -> KHGWNWRPLS (in isoform 3)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_021604"
FT VAR_SEQ 204..1909
FT /note="Missing (in isoform 3)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_021605"
FT VAR_SEQ 365..1683
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.4"
FT /id="VSP_021606"
FT VARIANT 250
FT /note="R -> Q (in dbSNP:rs58963837)"
FT /id="VAR_061686"
FT VARIANT 600
FT /note="S -> T (in dbSNP:rs17325719)"
FT /id="VAR_051220"
FT VARIANT 937
FT /note="V -> I (in dbSNP:rs12611515)"
FT /id="VAR_051221"
FT VARIANT 977
FT /note="I -> T (in dbSNP:rs12691830)"
FT /id="VAR_051222"
FT VARIANT 1093
FT /note="N -> Y (in dbSNP:rs16841277)"
FT /id="VAR_051223"
FT VARIANT 1260
FT /note="P -> Q (in dbSNP:rs13016342)"
FT /id="VAR_051224"
FT VARIANT 1403
FT /note="V -> A (in dbSNP:rs2278752)"
FT /id="VAR_051225"
FT CONFLICT 931..932
FT /note="PP -> QS (in Ref. 5; BAA22433)"
FT /evidence="ECO:0000305"
FT CONFLICT 948
FT /note="S -> P (in Ref. 5; BAA22433)"
FT /evidence="ECO:0000305"
FT CONFLICT 1018
FT /note="T -> S (in Ref. 5; BAA22433)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1909 AA; 208537 MW; 74CE34DF3ED05A29 CRC64;
MEGKRQLEKR DFGKRLSLDS SLVEYMDSNK YIEHLLTQLE EQHRSLWREK LAVARLQREV
AQRTSEGAMH EKLIHELEEE RHLRLQSEKR LQEVTLESER NRIQMRSLQQ QFSRMEETVR
NLLQSQGSPE QKKEETVNIM VYQEKLSEEE RKHKEALEDL HMVVDEDSRS ESSSTDEGKE
KTKLLLERLK ALEAENSALA LENENQREQY ERCLDEVANQ VVQALLTQKD LREECVKLKT
RVFDLEQQNR TLSILFQQRV RPTSDLLLQK LHSRLLDLSS GDLLSEVERN RSLTQSRTDA
EVHEHQLNTK SALKCPGLGA VIPGHLCPRN SYSSSSELSL SSTCSEYSSG SSYTWHDGKN
LRKRQSSQNW DKRLSIDSSL PSGFASPTNE LPPTRIKESH ILEGLRKLQK RKVLLEPPSV
ITKWGYKDCM NSNEGIYSPG IKSSSLKEYP PCKTADLGSP CKEPHKTFVY DLDSHVDADD
DPSTLALLQA VPNQSCRPHG SKLTHSVSDS LFGWETNRKH FLEGTSSVYP KERPEKLTSC
ASSCPLEMKL CPSVQTPQVQ RERGPQGQGH GRMALNLQLS DTDDNETFDE LHIESSDEKS
PSDVSLAADT DKSVENLDVL VGFGKSLCGS PEEEEKQVPI PSETRPKTFS FIKQQRVVKR
TSSEECVTVI FDAEDGEPIE FSSHQTGVVT VTRNEISINS TPAGPKAEHT ELLPQGIACL
QPRAAARDYT FFKRSEEDTE KNIPKDNVDN VPRVSTESFS SRTVTQNPQQ QKLVKPTHNI
SCQSNSRSSA PMGIYQKQNL TKIPPRGKSS PQKSKLMEPE ATTLLPSSGL VTLEKSPALA
PGKLSRFMKT ESSGPLFELR SDPHIPKHSA QLPHSSRMPS RRDWVQCPKS QTPGSRSRPA
IESSDSGEPP TRDEHCGSGP EAGVKSPSPP PPPGRSVSLL ARPSYDYSPA PSSTKSETRV
PSETARTPFK SPLLKGISAP VISSNPATTE VQRKKPSVAF KKPIFTHPMP SPEAVIQTRC
PAHAPSSSFT VMALGPPKVS PKRGVPKTSP RQTLGTPQRD IGLQTPRISP STHEPLEMTS
SKSVSPGRKG QLNDSASTPP KPSFLGVNES PSSQVSSSSS SSSPAKSHNS PHGCQSAHEK
GLKTRLPVGL KVLMKSPQLL RKSSTVPGKH EKDSLNEASK SSVAVNKSKP EDSKNPASME
ITAGERNVTL PDSQAQGSLA DGLPLETALQ EPLESSIPGS DGRDGVDNRS MRRSLSSSKP
HLKPALGMNG AKARSHSFST HSGDKPSTPP IEGSGKVRTQ IITNTAERGN SLTRQNSSTE
SSPNKAPSAP MLESLPSVGR PSGHPSSGKG SLGSSGSFSS QHGSPSKLPL RIPPKSEGLL
IPPGKEDQQA FTQGECPSAN VAVLGEPGSD RRSCPPTPTD CPEALQSPGR TQHPSTFETS
STSKLETSGR HPDASATATD AVSSEAPLSP TIEEKVMLCI QENVEKGQVQ TKPTSVEAKQ
KPGPSFASWF GFRKSRLPAL SSRKMDISKT KVEKKDAKVL GFGNRQLKSE RKKEKKKPEL
QCETENELIK DTKSADNPDG GLQSKNNRRT PQDIYNQLKI EPRNRHSPVA CSTKDTFMTE
LLNRVDKKAA PQTESGSSNA SCRNVLKGSS QGSCLIGSSI STQGNHKKNM KIKADMEVPK
DSLVKEANEN LQEDEDDAVA DSVFQSHIIE SNCQMRTLDS GIGTFPLPDS GNRSTGRYLC
QPDSPEDAEP LLPLQSALSA VSSMRAQTLE REVPSSTDGQ RPADSAIVHS TSDPIMTARG
MRPLQSRLPK PASSGKVSSQ KQNEAEPRPQ TCSSFGYAED PMASQPLPDW GSEVAATGTQ
DKAPRMCTYS ASGGSNSDSD LDYGDNGFGA GRGQLVKALK SAAPEIETT
