ID   A13_VAR67               Reviewed;          68 AA.
AC   P0DSW1; P33838;
DT   16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT   16-OCT-2019, sequence version 1.
DT   23-FEB-2022, entry version 6.
DE   RecName: Full=Virion membrane protein A13;
GN   ORFNames=A13L;
OS   Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=587200;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8384129; DOI=10.1016/0014-5793(93)80041-r;
RA   Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S.;
RT   "Genes of variola and vaccinia viruses necessary to overcome the host
RT   protective mechanisms.";
RL   FEBS Lett. 319:80-83(1993).
CC   -!- FUNCTION: Essential for the encapsidation of DNA into immature virions
CC       (IV) and the subsequent maturation of IV into mature virions (MV).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}. Note=The mature virion is located in
CC       the cytoplasm of infected cells and is probably released by cell lysis.
CC       {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae A13 family. {ECO:0000305}.
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DR   EMBL; X69198; CAA49058.1; -; Genomic_DNA.
DR   PIR; E36849; E36849.
DR   RefSeq; NP_042161.1; NC_001611.1.
DR   SMR; P0DSW1; -.
DR   GeneID; 1486488; -.
DR   KEGG; vg:1486488; -.
DR   Proteomes; UP000002060; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR009236; Chordopox_A13L.
DR   Pfam; PF05961; Chordopox_A13L; 1.
PE   2: Evidence at transcript level;
KW   Late protein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Virion.
FT   CHAIN           1..68
FT                   /note="Virion membrane protein A13"
FT                   /id="PRO_0000099240"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        22..68
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   68 AA;  7541 MW;  15BB909719033147 CRC64;
     MIGILLLIGI CVAVTVAILY AMYNKIKNSQ NPSPNVNLPP PETRNTRFVN NLEKDHISSL
     YNLVKSSV