ID   A11_VACCA               Reviewed;         318 AA.
AC   Q76RB8;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   07-APR-2021, entry version 33.
DE   RecName: Full=Protein A11;
GN   OrderedLocusNames=MVA122R, ACAM3000_MVA_122; ORFNames=A11R;
OS   Vaccinia virus (strain Ankara) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=126794;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9601507; DOI=10.1006/viro.1998.9123;
RA   Antoine G., Scheiflinger F., Dorner F., Falkner F.G.;
RT   "The complete genomic sequence of the modified vaccinia Ankara strain:
RT   comparison with other orthopoxviruses.";
RL   Virology 244:365-396(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate Acambis 3000;
RA   Esposito J.J., Frace M., Sammons S.A., Olsen-Rasmussen M.S., Osborne J.,
RA   Khristova M., Wohlhueter R.M.;
RL   Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for viral crescent formation early during virus
CC       morphogenesis. {ECO:0000250}.
CC   -!- SUBUNIT: Homomultimer. Interacts with A32. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000250}. Note=Localizes to
CC       the cytoplasmic viral factory. Not incorporated into virus particles.
CC       Does not seem to be a transmembrane protein (By similarity).
CC       {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC   -!- PTM: Phosphorylated by a F10-independent mechanism. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the poxviridae A11 family. {ECO:0000305}.
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DR   EMBL; U94848; AAB96521.1; -; Genomic_DNA.
DR   EMBL; AY603355; AAT10520.1; -; Genomic_DNA.
DR   SMR; Q76RB8; -.
DR   Proteomes; UP000159908; Genome.
DR   Proteomes; UP000172909; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007755; Poxvirus_A11.
DR   Pfam; PF05061; Pox_A11; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Host cytoplasm; Late protein; Phosphoprotein.
FT   CHAIN           1..318
FT                   /note="Protein A11"
FT                   /id="PRO_0000099230"
FT   COILED          145..172
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   318 AA;  36135 MW;  96A663C5A2477F64 CRC64;
     MTTVPVTDIQ NDLITEFSED NYPSNKNYEI TLRQMSILTH VNNVVDREHN AAVVSSPEEI
     SSQLNEDLFP DDDSPATIIE RVQPHTTIID DTPPPTFRRE LLISEQRQQR EKRFNITVSK
     NAEAIMESRS MISSMPTQTP SLGVVYDKDK RIQMLEDEVV NLRNQRSNTK SSDNLDNFTR
     ILFGKTPYKS TEVNKRIAIV NYANLNGSPL SVEDLDVCSE DEIDRIYKTI KQYHESRKRK
     IIVTNVIIIV INIIEQALLK LGFEEIKGLS TDITSEIIDV EIGDDCDAVA SKLGIGNSPV
     LNIVLFILKI FVKRIKII