ID   MUKE_ECOL6              Reviewed;         225 AA.
AC   Q8FJA3;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 2.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Chromosome partition protein MukE {ECO:0000255|HAMAP-Rule:MF_01802};
GN   Name=mukE {ECO:0000255|HAMAP-Rule:MF_01802}; OrderedLocusNames=c1065;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Involved in chromosome condensation, segregation and cell
CC       cycle progression. May participate in facilitating chromosome
CC       segregation by condensation DNA from both sides of a centrally located
CC       replisome during cell division. Probably acts via its interaction with
CC       MukB and MukF. {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SUBUNIT: Interacts, and probably forms a ternary complex, with MukF and
CC       MukB. The complex formation is stimulated by calcium or magnesium.
CC       {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01802}. Note=Restricted to the nucleoid region.
CC       {ECO:0000255|HAMAP-Rule:MF_01802}.
CC   -!- SIMILARITY: Belongs to the MukE family. {ECO:0000255|HAMAP-
CC       Rule:MF_01802}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN79533.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE014075; AAN79533.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; Q8FJA3; -.
DR   SMR; Q8FJA3; -.
DR   STRING; 199310.c1065; -.
DR   PRIDE; Q8FJA3; -.
DR   EnsemblBacteria; AAN79533; AAN79533; c1065.
DR   KEGG; ecc:c1065; -.
DR   eggNOG; COG3095; Bacteria.
DR   HOGENOM; CLU_1146408_0_0_6; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.2250; -; 1.
DR   Gene3D; 1.10.10.2260; -; 1.
DR   HAMAP; MF_01802; MukE; 1.
DR   InterPro; IPR042037; MukE_C.
DR   InterPro; IPR042038; MukE_N.
DR   InterPro; IPR007385; Scp_MukE.
DR   Pfam; PF04288; MukE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   DNA condensation.
FT   CHAIN           1..225
FT                   /note="Chromosome partition protein MukE"
FT                   /id="PRO_0000206793"
FT   REGION          197..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   225 AA;  25957 MW;  C4AD5E59ECC5D229 CRC64;
     MPVKLAQALA NPLFPALDSA LRSGRHIGLD ELDNHAFLMD FQEYLEEFYA RYNVELIRAP
     EGFFYLRPRS TTLIPRSVLS ELDMMVGKIL CYLYLSPERL ANEGIFTQQE LYDELLTLAD
     EAKLLKLVNN RSTGSDVDRQ KLQEKVRSSL NRLRRLGMVW FMGHDSSKFR ITESVFRFGA
     DVRAGDDPRE AQRRLIRDGE AMPIENHLQL NDETEESQPD SGEEE