MP702_ARATH
ID MP702_ARATH Reviewed; 634 AA.
AC Q8L7S4; Q3MQ34; Q9FXK0;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Microtubule-associated protein 70-2;
DE Short=AtMAP70-2;
DE AltName: Full=70 kDa microtubule-associated protein 2;
GN Name=MAP70.2; OrderedLocusNames=At1g24764; ORFNames=F5A9.19;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=15860013; DOI=10.1111/j.1365-313x.2005.02393.x;
RA Korolev A.V., Chan J., Naldrett M.J., Doonan J.H., Lloyd C.W.;
RT "Identification of a novel family of 70 kDa microtubule-associated proteins
RT in Arabidopsis cells.";
RL Plant J. 42:547-555(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- FUNCTION: Plant-specific protein that interact with microtubules.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC Note=Associated to microtubules.
CC -!- SIMILARITY: Belongs to the MAP70 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG03117.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAJ31079.1; Type=Frameshift; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM086439; CAJ31079.1; ALT_FRAME; mRNA.
DR EMBL; AC004133; AAG03117.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE30561.1; -; Genomic_DNA.
DR EMBL; AY128287; AAM91095.1; -; mRNA.
DR EMBL; BT000826; AAN33201.1; -; mRNA.
DR RefSeq; NP_173873.5; NM_102311.7.
DR AlphaFoldDB; Q8L7S4; -.
DR SMR; Q8L7S4; -.
DR BioGRID; 24320; 7.
DR IntAct; Q8L7S4; 7.
DR STRING; 3702.AT1G24764.1; -.
DR iPTMnet; Q8L7S4; -.
DR PaxDb; Q8L7S4; -.
DR PRIDE; Q8L7S4; -.
DR ProteomicsDB; 250942; -.
DR EnsemblPlants; AT1G24764.1; AT1G24764.1; AT1G24764.
DR GeneID; 839083; -.
DR Gramene; AT1G24764.1; AT1G24764.1; AT1G24764.
DR KEGG; ath:AT1G24764; -.
DR Araport; AT1G24764; -.
DR TAIR; locus:2826057; AT1G24764.
DR eggNOG; ENOG502QTPA; Eukaryota.
DR HOGENOM; CLU_023069_0_0_1; -.
DR InParanoid; Q8L7S4; -.
DR PhylomeDB; Q8L7S4; -.
DR PRO; PR:Q8L7S4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8L7S4; baseline and differential.
DR Genevisible; Q8L7S4; AT.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; ISS:TAIR.
DR GO; GO:0008017; F:microtubule binding; ISS:TAIR.
DR GO; GO:0007010; P:cytoskeleton organization; TAS:TAIR.
DR InterPro; IPR009768; MAP70.
DR PANTHER; PTHR31246; PTHR31246; 1.
DR Pfam; PF07058; MAP70; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Cytoplasm; Cytoskeleton; Microtubule; Reference proteome.
FT CHAIN 1..634
FT /note="Microtubule-associated protein 70-2"
FT /id="PRO_0000409458"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..494
FT /note="Required for targeting to microtubules"
FT /evidence="ECO:0000250"
FT REGION 393..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 594..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 74..392
FT /evidence="ECO:0000255"
FT COILED 532..601
FT /evidence="ECO:0000255"
FT COMPBIAS 1..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..468
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..517
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 605..619
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 634 AA; 70207 MW; 12321E079BEA3E7C CRC64;
MSDVSGDGDL SATVTEHEVT PQPPVSSATY PSLTVSASYK ESSGGKSSSK RRPIRPSFDA
AADNEFITLL HGSDPVKVEL NRLENEVRDK DRELGEANAE IKALRLSERQ REKAVEELTE
ELTKLDEKLK LTESILESKN LEIKKINEEK KASMAAQFAA EATLRRVHAA QKDDDMPPIE
AILAPLEAEL KLARSEIGKL QEDNRALDRL TKSKEAALLE AERTVEAAMA KAAMVDDLQN
KNQELMKQIE ICQEENKILD RMHRQKVAEV EKLTQTVREL EEAVLAGGAA ANAVRDYQRK
FQEMNEERKT LDRELARAKV TANRVATVVA NEWKDGNDKV MPVKQWLEER RFLQGEMQQL
RDKLAITDRA AKSEAQLKEK FQLRLKVLEE TLRGTSSSAT RNTPEARSMS NGPSRRQSLG
GAENLQKFTS NGALSKKAPA SQMRHSLSIN STSVLKNAKG TSKSFDGGTR SVDRGKALLN
GPGNYSFNKA TDDSKEAESG NGWKENSEEK PQSEDPEAAT EDSVPGVLYD LLQKEVVSLR
KASNEKDQSL KDKDDAIEML AKKVETLTKA MEVEAKKMRR EVAAMEKEVA AMRVEKDQDA
RAKRFSNSKS PSNTAQILAG RAAGRSGGLT KSTQ
