ID   MDV1_MAGO7              Reviewed;         661 AA.
AC   A4RJV3; G4MUW9;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-JAN-2012, sequence version 3.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Mitochondrial division protein 1;
GN   Name=MDV1; ORFNames=MGG_01711;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: Involved in mitochondrial fission. Acts as an adapter protein
CC       required to form mitochondrial fission complexes. Formation of these
CC       complexes is required to promote constriction and fission of the
CC       mitochondrial compartment at a late step in mitochondrial division (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Cytoplasmic side
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat MDV1/CAF4 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM001232; EHA54899.1; -; Genomic_DNA.
DR   RefSeq; XP_003714706.1; XM_003714658.1.
DR   AlphaFoldDB; A4RJV3; -.
DR   SMR; A4RJV3; -.
DR   STRING; 318829.MGG_01711T0; -.
DR   EnsemblFungi; MGG_01711T0; MGG_01711T0; MGG_01711.
DR   GeneID; 2679351; -.
DR   KEGG; mgr:MGG_01711; -.
DR   VEuPathDB; FungiDB:MGG_01711; -.
DR   eggNOG; KOG4155; Eukaryota.
DR   HOGENOM; CLU_012350_1_1_1; -.
DR   InParanoid; A4RJV3; -.
DR   OMA; IVGVWTC; -.
DR   OrthoDB; 927943at2759; -.
DR   PHI-base; PHI:6135; -.
DR   PHI-base; PHI:6636; -.
DR   Proteomes; UP000009058; Chromosome 2.
DR   GO; GO:0030014; C:CCR4-NOT complex; ISS:PAMGO_MGG.
DR   GO; GO:0030015; C:CCR4-NOT core complex; ISS:PAMGO_MGG.
DR   GO; GO:0005741; C:mitochondrial outer membrane; ISS:PAMGO_MGG.
DR   GO; GO:0005739; C:mitochondrion; ISS:PAMGO_MGG.
DR   GO; GO:0051020; F:GTPase binding; ISS:PAMGO_MGG.
DR   GO; GO:0006354; P:DNA-templated transcription, elongation; ISS:PAMGO_MGG.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; ISS:PAMGO_MGG.
DR   GO; GO:0000266; P:mitochondrial fission; ISS:PAMGO_MGG.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; ISS:PAMGO_MGG.
DR   GO; GO:0006402; P:mRNA catabolic process; ISS:PAMGO_MGG.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:PAMGO_MGG.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 4.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 3.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Membrane; Mitochondrion; Mitochondrion outer membrane;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..661
FT                   /note="Mitochondrial division protein 1"
FT                   /id="PRO_0000330107"
FT   REPEAT          317..358
FT                   /note="WD 1"
FT   REPEAT          359..396
FT                   /note="WD 2"
FT   REPEAT          437..476
FT                   /note="WD 3"
FT   REPEAT          478..498
FT                   /note="WD 4"
FT   REPEAT          499..541
FT                   /note="WD 5"
FT   REPEAT          544..583
FT                   /note="WD 6"
FT   REPEAT          585..620
FT                   /note="WD 7"
FT   REPEAT          622..660
FT                   /note="WD 8"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          135..170
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          244..267
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          275..294
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          397..416
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          211..254
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   661 AA;  73100 MW;  67245E3E93858FA5 CRC64;
     MASPEDENPF QDDPGQEDED GSILSPRGLE AFSRKVTTTA SHLMGPVVDP SSSGHYQSAM
     TEVQKHLRRP NLQRSMFSMA RTTPSDLVRS KLSTREIQHR ALAHVPDDML ANIPEDDNNS
     YSLFQGFQAS FPELTDEGKK HRRRVSRGRK LLDEGPTTPE NGTTGLQKLR KERASMSHEL
     EMLGIRKNMA SSEIREIDIK IANLHGMRRI ILERLAALEQ EETLLEHDLM EVEARVEDAQ
     MLADEAESTA QQSSPRDTDD ADAEDNDGFM SQSIYEKIPS AASTPSKSRK PRIVRRKSMA
     VLHEHFEPGT SIRELRAHQD CITAMDFDAP FGTLVSAAMD DSVKVWDLNA GRCIGSLEGH
     TASVRALQVE DNILATGSRD ATVRLWDLSK AHYDPHGSHY NGGDDDDDAM AFENPDDQPV
     DPPAGSMADC PLFTLSSHMD EVTALHFKGD TLVSGSSDKT IRQWDLVKGR CVQTLDVMWA
     AAQASVSLGT GDGAWRQTAR SQAEDADFVG AVQVFDAALA CGTADGMVRL WDLRSGQVHR
     NLVGHTGPVT ALQFDNMHLV TGSHDRSIRI WDLRTGSIFD AFAYDHPVTS MMFDARRIVS
     AAGEDVVKVY DKVESRQWDC GAGIKAAEEM KNPPAIVERV RIRDGYMVEG RRDGIVGIWT
     C